Evidence map›Paper›PMID 31037949›Full record

ArticleAntioxidants & redox signaling2019

Redox-Dependent Loss of Flavin by Mitochondrial Complex I in Brain Ischemia/Reperfusion Injury.

Anna Stepanova, Sergey Sosunov, Zoya Niatsetskaya, Csaba Konrad, Anatoly A Starkov, Giovanni Manfredi, Ilka Wittig, Vadim Ten, Alexander Galkin

Open access · greenAbstract read
In one paragraph

Article in Antioxidants & redox signaling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Rescuing Ischemic Brain Injury by Rewiring Mitochondrial Electron Flow.bioRxiv : the preprint server for biology · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Sex-dependent differences in macaque brain mitochondria.Biochimica et biophysica acta. Bioenergetics · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. A Spectrofluorometric Method for Real-Time Graft Assessment and Patient Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Anna Stepanova1Division of Neonatology, Department of Pediatrics, Columbia University, New York, New York.
Sergey Sosunov1Division of Neonatology, Department of Pediatrics, Columbia University, New York, New York.
Zoya Niatsetskaya1Division of Neonatology, Department of Pediatrics, Columbia University, New York, New York.
Csaba Konrad2Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York.
Anatoly A Starkov2Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York.
Giovanni Manfredi2Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York.
Ilka Wittig3Functional Proteomics, SFB815 Core Unit, Medical School, Goethe University, Frankfurt, Germany.
Vadim Ten1Division of Neonatology, Department of Pediatrics, Columbia University, New York, New York.
Alexander Galkin1Division of Neonatology, Department of Pediatrics, Columbia University, New York, New York.
Columbia University · USCornell University · USGoethe University Frankfurt · DE

Funding

TRANSCRIPTIONAL RESPONSES TO MITOCHONDRIAL DYSFUNCTIONP01AG014930 · NIA · WINIFRED MASTERSON BURKE MED RES INST · PI GIBSON, GARY E · 1999 to 2020
$30.7M
Mitochondrial complex-I as a target for metabolic resuscitation in perinatal hypoxic-ischemic brain injuryR01NS100850 · NINDS · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI TEN, VADIM S · 2017 to 2021
$2.0M
Estrogen receptor beta and mitochondrial permeability transition in Ca2+-induced neuronal injuryR01NS095692 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IADECOLA, COSTANTINO, MANFREDI, GIOVANNI · 2016 to 2020
$1.9M
NIA NIH HHS P01 AG014930NINDS NIH HHS R01 NS095692NINDS NIH HHS R01 NS100850
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Oxidation-ReductionAnimalsAnimals, NewbornElectron Transport Complex IFlavin MononucleotideFlavinsHydrogen PeroxideHypoxia-Ischemia, BrainMiceMitochondriaOxidative StressOxygenReactive Oxygen SpeciesReperfusion InjuryStructure-Activity RelationshipElectron Transport Complex IFlavin MononucleotideFlavinsHydrogen PeroxideOxygenReactive Oxygen Speciesflavin mononucleotideischemia/reperfusion injurymitochondrial complex Ireverse electron transfersecondary energy failure

Identifiers

PMID31037949
PMCPMC6657304
OpenAlexW2943168031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.