Evidence map›Paper›PMID 31037867›Full record

ArticleAnnals of laboratory medicine2019

Comparison of cobas

A Lum Han, Hak Ryul Kim, Keum Ha Choi, Ki Eun Hwang, Mengyu Zhu, Yuya Huang, Moxin Wu, Young Jin Lee, Min Cheol Park, Ji Hyun Cho and 1 more

Open access · diamondAbstract readComparative Study
In one paragraph

Article in Annals of laboratory medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Advances in laboratory medicine · 2025
    Article
  2. Integrating ctDNA testing forAdvances in laboratory medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

A Lum Han *Department of Family Medicine, School of Medicine, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0002-6509-7953
Hak Ryul Kim *Department of Internal Medicine, School of Medicine, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0002-8738-4320
Keum Ha ChoiDepartment of Pathology, School of Medicine, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0001-8617-4869
Ki Eun HwangDepartment of Internal Medicine, School of Medicine, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0002-9213-5775
Mengyu ZhuDepartment of Laboratory Medicine and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0001-9795-9039
Yuya HuangDepartment of Laboratory Medicine and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0002-9096-027X
Moxin WuDepartment of Laboratory Medicine and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0001-5823-3657
Young Jin LeeDepartment of Laboratory Medicine and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0002-6503-221X
Min Cheol ParkDepartment of Oriental Medical Ophthalmology & Otolaryngology & Dermatology, College of Oriental Medicine, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0003-0448-4148
Ji Hyun ChoDepartment of Laboratory Medicine and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0002-6504-7892
Do Sim ParkDepartment of Laboratory Medicine and Institute of Wonkwang Medical Science, School of Medicine, Wonkwang University, Iksan, Korea.ORCID https://orcid.org/0000-0002-6001-4223
Wonkwang University · KR

Funding

National Research Foundation of Korea NRF-2015M3A9E3051054National Research Foundation of Korea NRF-2016R1D1A1 B04935786
6 · The paper itself

Abstract

backgroundPlasma epidermal growth factor receptor (

methodsWe analyzed 156 plasma and PE-SUP samples (31 paired samples) from 116 individuals. We compared the kits in terms of accuracy, assessed genotype concordance (weighted κ with 95% confidence intervals), and calculated Spearman's rho between semi-quantitatively measured

resultscobasv2 tended to have higher accuracy than Mutyper (73% vs 69%,

conclusionsThe kits have similar performance in terms of

Indexed as

AdultAgedAged, 80 and overDNAErbB ReceptorsFemaleGenotypeHumansMaleMiddle AgedMutationPleural EffusionPolymerase Chain ReactionReagent Kits, DiagnosticYoung AdultDNAErbB ReceptorsReagent Kits, Diagnosticcobas EGFR Mutation test v2Epidermal growth factor receptorMutationPANAMutyper-R-EGFRPlasmaPleural effusion supernatant

Identifiers

PMID31037867
PMCPMC6502955
OpenAlexW2942885574

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.