Evidence map›Paper›PMID 31037800›Full record

ArticleJournal of neuroimaging : official journal of the American Society of Neuroimaging2019

A Multi-Atlas Label Fusion Tool for Neonatal Brain MRI Parcellation and Quantification.

Yoshihisa Otsuka, Linda Chang, Yukako Kawasaki, Dan Wu, Can Ceritoglu, Kumiko Oishi, Thomas Ernst, Michael Miller, Susumu Mori, Kenichi Oishi

Open access · greenAbstract read
In one paragraph

Article in Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Yoshihisa OtsukaDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Linda ChangDepartment of Medicine, School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
Yukako KawasakiDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Dan WuDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Can CeritogluCenter for Imaging Science, Johns Hopkins University, Baltimore, MD, USA.
Kumiko OishiCenter for Imaging Science, Johns Hopkins University, Baltimore, MD, USA.
Thomas ErnstDepartment of Medicine, School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
Michael MillerCenter for Imaging Science, Johns Hopkins University, Baltimore, MD, USA.
Susumu MoriDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kenichi OishiDepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-1200-8611
Johns Hopkins University · USUniversity of Hawaiʻi at Mānoa · USKennedy Krieger Institute · US

Funding

Imaging Studies in Neurotoxicity and NeurodevelopmentU54NS056883 · NINDS · UNIVERSITY OF HAWAII AT MANOA · PI CHANG, LINDA · 2007 to 2011
$8.4M
Development of quantitative MRI DTI analysis tool for preterm neonateR01HD065955 · NICHD · JOHNS HOPKINS UNIVERSITY · PI OISHI, KENICHI · 2011 to 2015
$2.3M
Neuroimaging and Mentoring in Drug Abuse ResearchK24DA016170 · NIDA · UNIVERSITY OF HAWAII AT MANOA · PI CHANG, LINDA · 2003 to 2013
$1.8M
NICHD NIH HHS R01 HD065955NIDA NIH HHS K24 DA016170NINDS NIH HHS U54 NS056883
6 · The paper itself

Abstract

Structure-by-structure analysis, in which the brain magnetic resonance imaging (MRI) is parcellated based on its anatomical units, is widely used to investigate chronological changes in morphology or signal intensity during normal development, as well as to identify the alterations seen in various diseases or conditions. The multi-atlas label fusion (MALF) method is considered a highly accurate parcellation approach, and anticipated for clinical application to quantitatively evaluate early developmental processes. However, the current MALF methods, which are designed for neonatal brain segmentations, are not widely available. In this study, we developed a T1-weighted, neonatal, multi-atlas repository and integrated it into the MALF-based brain segmentation tools in the cloud-based platform, MRICloud. The cloud platform ensures users instant access to the advanced MALF tool for neonatal brains, with no software or installation requirements for the client. The Web platform by braingps.mricloud.org will eliminate the dependence on a particular operating system (eg, Windows, Macintosh, or Linux) and the requirement for high computational performance of the user's computers. The MALF-based, fully automated, image parcellation could achieve excellent agreement with manual parcellation, and the whole and regional brain volumes quantified through this method demonstrated developmental trajectories comparable to those from a previous publication. This solution will make the latest MALF tools readily available to users, with minimum barriers, and will expedite and accelerate advancements in developmental neuroscience research, neonatology, and pediatric neuroradiology.

Indexed as

BrainBrain MappingHumansImage Processing, Computer-AssistedInfant, NewbornMagnetic Resonance ImagingSoftwareBrainMRImulti-atlasneonateparcellation

Identifiers

PMID31037800
PMCPMC6609486
OpenAlexW2943132664

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.