Evidence map›Paper›PMID 31037650›Full record

ArticleNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2019

Nucleic Acid Therapeutics for Neurological Diseases.

Jonathan K Watts, Robert H Brown, Anastasia Khvorova

Abstract readEditorial
In one paragraph

Article in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
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  9. Length Polymorphism and Methylation Status of UPS29 Minisatellite of theInternational journal of molecular sciences · 2020
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jonathan K WattsRNA Therapeutics Institute, UMass Medical School, Worcester, Massachusetts, 01605, USA. jonathan.watts@umassmed.edu.ORCID 0000-0001-5706-1734
Robert H BrownRNA Therapeutics Institute, UMass Medical School, Worcester, Massachusetts, 01605, USA.
Anastasia KhvorovaRNA Therapeutics Institute, UMass Medical School, Worcester, Massachusetts, 01605, USA.

Funding

Expanding the chemical diversity of therapeutic oligonucleotides to treat neurodegenerative disordersR01NS104022 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ANASTASIA KHVOROVA · 2017 to 2026
$6.0M
Next-generation antisense therapeutics for ALS and frontotemporal dementiaR01NS111990 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Robert H Brown, Jonathan K Watts · 2019 to 2026
$5.2M
Exosome based therapeutics in Huntington's diseaseUH3TR000888 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ARONIN, NEIL, KHVOROVA, ANASTASIA · 2015 to 2017
$3.0M
Enhancing CRISPR Gene Editing in Somatic Tissues by Chemical Modification of Guides and DonorsUG3TR002668 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KHVOROVA, ANASTASIA, SONTHEIMER, ERIK J. · 2018 to 2020
$2.5M
High Throughput Screening for Compounds to Mitigate Toxicity of FUS/TLS & SOD1R01NS079836 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BROWN, ROBERT H. · 2012 to 2015
$1.9M
Silencing C9or72 with rAAV Mediated RNAiR01NS088689 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BROWN, ROBERT H., MUELLER, CHRISTIAN · 2014 to 2017
$1.6M
Mid-Scale RNA Synthesis, Purification and Quality Control SystemS10OD020012 · OD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KHVOROVA, ANASTASIA · 2015 to 2015
$563k
NCATS NIH HHS UG3 TR002668NCATS NIH HHS UH3 TR000888NIH HHS S10 OD020012NINDS NIH HHS R01 NS079836NINDS NIH HHS R01 NS088689NINDS NIH HHS R01 NS104022NINDS NIH HHS R01 NS111990
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsHumansNervous System DiseasesNucleic AcidsOligonucleotidesNucleic AcidsOligonucleotides

Identifiers

PMID31037650
PMCPMC6554381

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.