Evidence map›Paper›PMID 31037509›Full record

ReviewIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2019

Mucosal healing in inflammatory bowel disease: Expanding horizon.

Jimil Shah, Manik Lal Thakur, Usha Dutta

Abstract readReview
PubMed Publisher
In one paragraph

Review in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jimil ShahDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
Manik Lal ThakurDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India.
Usha DuttaDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India. ushadutta@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Management of inflammatory bowel diseases has witnessed paradigm shift from 5-aminosalicylic acid and glucocorticoids to various immunosuppressant and biological agents. Targets of therapy have also been changed drastically from symptomatic improvement to mucosal, histological healing, and recently transmural healing. Mucosal healing is associated with reduced need of steroid therapy, hospitalization, and surgery. However, whether mucosal healing alters the natural history of disease remains to be proven. Though assessment of mucosal healing is traditionally done by endoscopic examination, newer tests like fecal calprotectin, capsule endoscopy, and magnetic resonance enterography have also shown promising results. Various immunosuppressants and biologicals are the main therapy being used to achieve mucosal healing. This review focuses on the need for achieving mucosal healing, its long-term benefits, various methods and algorithm for diagnosis, and achievement of mucosal healing.

Indexed as

Wound HealingBiological FactorsCapsule EndoscopyEndoscopy, GastrointestinalGlucocorticoidsHumansImmunosuppressive AgentsInflammatory Bowel DiseasesIntestinal MucosaLeukocyte L1 Antigen ComplexMagnetic Resonance ImagingMesalamineBiological FactorsGlucocorticoidsImmunosuppressive AgentsLeukocyte L1 Antigen ComplexMesalamineHistological healingInflammatory bowel diseaseMucosal healingTarget to treat approach

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.