Evidence map›Paper›PMID 31037426›Full record

ReviewCalcified tissue international2019

Fibrous Dysplasia of Bone and McCune-Albright Syndrome: A Bench to Bedside Review.

Iris Hartley, Maria Zhadina, Micheal T Collins, Alison M Boyce

Open access · greenAbstract readReview
In one paragraph

Review in Calcified tissue international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 98 citations in OpenAlex.

  1. No overshoot of bone turnover after withdrawal of denosumab treatment of adults with Langerhans cell histiocytosis: a prospective clinical trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Trial
  2. Article
  3. Fibrous dysplasia: clinical and pathologic characteristics, surgical approaches, and outcomes in a large Italian cohort.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
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  14. Pain in fibrous dysplasia: identifying nociceptive mechanisms in a preclinical model.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Article
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  16. Article
  17. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Iris Hartley *Skeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Building 30 Room 228 MSC 4320, Bethesda, MD, 20892, USA.
Maria Zhadina *Skeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Building 30 Room 228 MSC 4320, Bethesda, MD, 20892, USA.
Micheal T CollinsSkeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Building 30 Room 228 MSC 4320, Bethesda, MD, 20892, USA.
Alison M BoyceSkeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Building 30 Room 228 MSC 4320, Bethesda, MD, 20892, USA. boyceam@mail.nih.gov.ORCID http://orcid.org/0000-0003-2987-3887
National Institutes of Health · US

Funding

Skeletal Disorders and Mineral Homeostasis SectionZIADE000649 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI COLLINS, MICHAEL · 2009 to 2025
$32.8M
Clinical Studies Of Skeletal DiseasesZ01DE000649 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI COLLINS, MICHAEL · 1995 to 2008
$2.7M
Intramural NIH HHS Z01 DE000649Intramural NIH HHS Z99 DE999999
6 · The paper itself

Abstract

Fibrous dysplasia is an uncommon mosaic disorder in which bone is replaced by structurally unsound fibro-osseous tissue. It is caused by the sporadic post-zygotic activating mutations in GNAS, resulting in dysregulated Gα

Indexed as

MutationAnimalsBone and BonesCafe-au-Lait SpotsCartilage DiseasesCell Transformation, NeoplasticChromograninsDisease ProgressionFibroblast Growth Factor-23Fibrous Dysplasia of BoneFibrous Dysplasia, PolyostoticGenetic Predisposition to DiseaseGTP-Binding Protein alpha Subunits, GsHumansInterleukin-6Signal TransductionChromograninsFGF23 protein, humanFibroblast Growth Factor-23GNAS protein, humanGTP-Binding Protein alpha Subunits, GsIL6 protein, humanInterleukin-6Bone disordersBone metabolismFGF23-mediated hypophosphatemiaMcCune–Albright syndrome

Identifiers

PMID31037426
PMCPMC6541017
OpenAlexW2943678774

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.