ArticleDysphagia2019
Alteration of Brain Functional Connectivity in Parkinson's Disease Patients with Dysphagia.
Article in Dysphagia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Acupuncture Therapy on Dysphagia in Patients with Parkinson's Disease: A Randomized Controlled Study.Chinese journal of integrative medicine · 2025Trial
- SimulScan and Partial Least Squares: Visualizing Swallowing Through Functional and Dynamic Imaging Correlations.Magnetic resonance in medicine · 2026Article
- Distinct brain susceptibility alteration pattern in Parkinson's disease with drooling: evidence from quantitative susceptibility mapping.Quantitative imaging in medicine and surgery · 2026Article
- Respiratory-Swallow Training and Variable Practice in Parkinson's Disease: A Clinical Trial Pilot Study.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2026Article
- Analysis of parkinson's disease patients with Gastrointestinal symptoms using structural and functional magnetic resonance imaging.Brain imaging and behavior · 2025Article
- SimulScan and Partial Least Squares: Visualizing swallowing through functional and dynamic imaging correlations.bioRxiv : the preprint server for biology · 2025Article
- Research advances in dysphagia animal models.Animal models and experimental medicine · 2025Review
- Exploring the Neuropsychological Correlates of Swallowing Disorders in People with Parkinson's Disease: a Cross-Sectional Study.Dysphagia · 2025Article
- A Systematic Review and Meta-Analysis of Non-Invasive Nerve Stimulation Interventions on Dysphagia in Patients with Parkinson's Disease.Neuropsychiatric disease and treatment · 2025Review
- rTMS improves dysphagia by inhibiting NLRP3 inflammasome activation and caspase-1 dependent pyroptosis in PD mice.NPJ Parkinson's disease · 2024Article
- Drooling disrupts the brain functional connectivity network in Parkinson's disease.CNS neuroscience & therapeutics · 2023Article
- Association of dysphagia with altered brain glucose metabolism in Parkinson's disease.CNS neuroscience & therapeutics · 2023Article
- Common and distinct roles of amygdala subregional functional connectivity in non-motor symptoms of Parkinson's disease.NPJ Parkinson's disease · 2023Article
- The Effect of Swallowing Action Observation Therapy on Resting fMRI in Stroke Patients with Dysphagia.Neural plasticity · 2023Article
- Increased activation of the caudate nucleus and parahippocampal gyrus in Parkinson's disease patients with dysphagia after repetitive transcranial magnetic stimulation: a case-control study.Neural regeneration research · 2022Article
- Pharyngeal Area Changes in Parkinson's Disease and Its Effect on Swallowing Safety, Efficiency, and Kinematics.Dysphagia · 2020Article
- Altered Functional Network Associated With Cognitive Performance in Early Parkinson Disease Measured by Eigenvector Centrality Mapping.Frontiers in aging neuroscience · 2020Article
Corrections and comments
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dysphagia is a common non-primary symptom of patients with Parkinson's disease. The aim of this study is to investigate the underlying alterations of brain functional connectivity in Parkinson's disease patients with dysphagia by resting-state functional magnetic resonance imaging. We recruited 13 Parkinson's disease patients with dysphagia and ten patients without dysphagia, diagnosed by videofluoroscopic study of swallowing. Another 13 age and sex-matched healthy subjects were recruited. Eigenvector centrality mapping was computed to identify functional connectivity alterations among these groups. Parkinson's disease patients with dysphagia had significantly increased functional connectivity in the cerebellum, left premotor cortex, the supplementary motor area, the primary motor cortex, right temporal pole of superior temporal gyrus, inferior frontal gyrus, anterior cingulate cortex and insula, compared with patients without dysphagia. This study suggests that functional connectivity changes in swallowing-related cortexes might contribute to the occurrence of dysphagia in Parkinson's disease patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.