ArticleThe Pan African medical journal2018
Predictors of post neonatal mortality in Western Kenya: a cohort study.
Article in The Pan African medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Prevalence and determinants of post-neonatal mortality in East Africa: a multilevel analysis of the recent demographic and health survey.Frontiers in pediatrics · 2025Article
- Article
- Comparative genomic and phenotypic characterization of invasive non-typhoidal Salmonella isolates from Siaya, Kenya.PLoS neglected tropical diseases · 2021Article
- Article
- Modelling mortality within 28 days among preterm infants at a tertiary hospital in Lusaka, Zambia: a retrospective review of hospital-based records.The Pan African medical journal · 2021Article
- Identifying Infants and Young Children at Risk of Unplanned Hospital Admissions and Clinic Visits in Dar es Salaam, Tanzania.The Pediatric infectious disease journal · 2020Article
- Development of a TB vaccine trial site in Africa and lessons from the Ebola experience.BMC public health · 2020Article
- Identifying Factors Associated with Neonatal Mortality in Sub-Saharan Africa using Machine Learning.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2020Article
- Successes and Misses of Global Health Development: Detecting Temporal Concept Drift of Under-5 Mortality Prediction Models with Bias Scan.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational ScienceArticle
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Authors and funding
4 authors at 3 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
introductionto determine the predictors of mortality in infants in Siaya, western Kenya, ahead of novel tuberculosis (TB) vaccine trials in the same population.
methodsin a study to determine tuberculosis incidence, 2900 infants aged 0-45 days, weighing ≥ 1700g were enrolled. Four monthly follow up visits were conducted for at least 12 months. HIV testing was done at six weeks of age. Free ancillary care was provided. Deaths were reported by parents, study staff and community workers. Cox proportional Hazard analysis was used to identify risk factors. The period of analysis commenced at six weeks old and was censored at 12 months of age.
resultsincluded in the analysis were 2528 infants with 2020 person years of follow up (pyo). There were 117 deaths (4.6 %). The post-neonatal mortality rate was 58 (95% CI: 48, 69) per 1000 pyo. In multivariate analysis, health facility births were protective against mortality (Hazard Ratio (HR) 0.54; 95% CI: 0.34, 0.84) and infant HIV infection at baseline was associated with increased mortality (HR 10.3; 95% CI: 6.40, 16.7). HIV uninfected infants born to HIV infected mothers had increased hazards of mortality (HR 1.73; 95% CI: 1.03, 2.90). Gender, weight at six weeks, maternal education and occupation were not significant predictors of mortality.
conclusioninfant mortality was high and was associated with being born outside a health facility, maternal HIV infection and HIV infection of the infant. Measures to decrease mother to child transmission and other HIV control measures need to be strengthened further to see incremental reductions in infant mortality.
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