Evidence map›Paper›PMID 31037154›Full record

ArticleTheranostics2019

Mitochondrial Transfer from Bone Marrow Mesenchymal Stem Cells to Motor Neurons in Spinal Cord Injury Rats via Gap Junction.

Heyangzi Li, Chao Wang, Teng He, Tengfei Zhao, Ying-Ying Chen, Yue-Liang Shen, Xiaoming Zhang, Lin-Lin Wang

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 157 papers.

0numbers the graph read from it
0cells of the map it votes in
157citing papers in PubMed
17.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

157 citing papers in PubMed, 299 citations in OpenAlex.

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  16. Mitochondrial transplant activates CaStem cell research & therapy · 2026
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97 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Heyangzi LiDepartment of Basic Medicine Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Chao WangDepartment of Basic Medicine Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Teng HeDepartment of Basic Medicine Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Tengfei ZhaoDepartment of Orthopedic Surgery, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.
Ying-Ying ChenDepartment of Basic Medicine Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Yue-Liang ShenDepartment of Basic Medicine Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Xiaoming ZhangDepartment of Basic Medicine Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Lin-Lin WangDepartment of Basic Medicine Sciences, Zhejiang University School of Medicine, Hangzhou 310058, China.
Zhejiang University · CNSecond Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have demonstrated that bone marrow mesenchymal stem cells (BMSCs) protect the injured neurons of spinal cord injury (SCI) from apoptosis while the underlying mechanism of the protective effect of BMSCs remains unclear. In this study, we found the transfer of mitochondria from BMSCs to injured motor neurons and detected the functional improvement after transplanting.

Indexed as

AnimalsApoptosisBone Marrow CellsCells, CulturedCell SurvivalCoculture TechniquesGap JunctionsMaleMesenchymal Stem CellsMesenchymal Stem Cell TransplantationMitochondriaMotor NeuronsRatsRats, Sprague-DawleyRecovery of FunctionSpinal Cordbone marrow stromal cellsgap junctionmitochondriaspinal cord injurytransfer

Identifiers

PMID31037154
PMCPMC6485285
OpenAlexW2924809867

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.