Evidence map›Paper›PMID 31037147›Full record

ArticleTheranostics2019

HMGB1-Induced p62 Overexpression Promotes Snail-Mediated Epithelial-Mesenchymal Transition in Glioblastoma Cells via the Degradation of GSK-3β.

Hong Li, Junjie Li, Guozhong Zhang, Qian Da, Lei Chen, Shishi Yu, Qiang Zhou, Zhijian Weng, Zong Xin, Linyong Shi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 84 citations in OpenAlex.

  1. Tumor-intrinsic TLR4 signaling as a context-dependent rheostat in glioblastoma.Journal of molecular medicine (Berlin, Germany) · 2026
    Review
  2. HMGB1: A Central Node in Cancer Therapy Resistance.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
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  14. Lipopolysaccharide (LPS) extracted fromMolecular medicine reports · 2023
    Article
  15. Review
  16. Article
  17. Function ofJournal of gastrointestinal oncology · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Hong LiDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Junjie LiDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Guozhong ZhangDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qian DaDepartment of Pathology, Ruijing Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Lei ChenDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Shishi YuEditorial Department of the Journal of Southern Medical University, Guangzhou, China.
Qiang ZhouDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhijian WengDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zong XinDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Linyong ShiDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Liyi MaDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Annie HuangBrain Tumor Research Center, SickKids Hospital, Toronto, Canada.
Songtao QiDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yuntao LuDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Nanfang Hospital · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell LineCell Line, TumorCell MovementEpithelial-Mesenchymal TransitionGlioblastomaGliomaGlycogen Synthase Kinase 3 betaHEK293 CellsHMGB1 ProteinHumansProteasome Endopeptidase ComplexSequestosome-1 ProteinSignal TransductionSnail Family Transcription FactorsTranscription FactorsGlycogen Synthase Kinase 3 betaHMGB1 ProteinHMGB1 protein, humanProteasome Endopeptidase ComplexSequestosome-1 ProteinSnail Family Transcription FactorsSQSTM1 protein, humanTranscription Factorsepithelial-to-mesenchymal transition (EMT)glioblastomaGSK-3βHMGB1p62

Identifiers

PMID31037147
PMCPMC6485286
OpenAlexW2924775478

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.