Evidence map›Paper›PMID 31037128›Full record

ArticleTheranostics2019

Pseurotin A Inhibits Osteoclastogenesis and Prevents Ovariectomized-Induced Bone Loss by Suppressing Reactive Oxygen Species.

Kai Chen, Pengcheng Qiu, Yu Yuan, Lin Zheng, Jianbo He, Chao Wang, Qiang Guo, Jacob Kenny, Qian Liu, Jinmin Zhao and 5 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers.

0numbers the graph read from it
0cells of the map it votes in
135citing papers in PubMed
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

135 citing papers in PubMed, 250 citations in OpenAlex.

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  15. Nrf2 signaling pathway: focus on oxidative stress in osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
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75 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Kai ChenSchool of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia.
Pengcheng QiuDepartment of Orthopedic Surgery, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Hangzhou, Zhejiang 310000, China.
Yu YuanSchool of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia.
Lin ZhengDepartment of Orthopedic Surgery, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Hangzhou, Zhejiang 310000, China.
Jianbo HeSchool of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia.
Chao WangSchool of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia.
Qiang GuoSchool of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia.
Jacob KennySchool of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia.
Qian LiuSchool of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia.
Jinmin ZhaoResearch Centre for Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi 530021, China.
Junhao ChenSchool of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia.
Jennifer TicknerSchool of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia.
Shunwu FanDepartment of Orthopedic Surgery, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Hangzhou, Zhejiang 310000, China.
Xianfeng LinDepartment of Orthopedic Surgery, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Hangzhou, Zhejiang 310000, China.
Jiake XuSchool of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia.
University of Western Australia · AUGuangxi Medical University · CNZhejiang University · CNGuangzhou University of Chinese Medicine · CNBlood Center of Zhejiang Province · CNCentral South University · CNSouth China Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntioxidantsBone ResorptionDisease Models, AnimalGene Expression ProfilingMiceOsteogenesisOvariectomyPyrrolidinonesReactive Oxygen SpeciesTreatment OutcomeAntioxidantspseurotinPyrrolidinonesReactive Oxygen SpeciesosteoclastosteoporosisPseurotin Areactive oxygen species

Identifiers

PMID31037128
PMCPMC6485188
OpenAlexW2916484820

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.