Evidence map›Paper›PMID 31036896›Full record

ArticleNature ecology & evolution2019

The genetic history of admixture across inner Eurasia.

Choongwon Jeong, Oleg Balanovsky, Elena Lukianova, Nurzhibek Kahbatkyzy, Pavel Flegontov, Valery Zaporozhchenko, Alexander Immel, Chuan-Chao Wang, Olzhas Ixan, Elmira Khussainova and 39 more

Abstract read
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Article in Nature ecology & evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed.

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  7. On the Edge of Empire: Paleogenomic Insights into Roman Dacia.bioRxiv : the preprint server for biology · 2026
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  10. Global patterns of natural selection inferred using ancient DNA.bioRxiv : the preprint server for biology · 2026
    Article
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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

49 authors.

Choongwon JeongDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany. jeong@shh.mpg.de.ORCID http://orcid.org/0000-0003-3049-2352
Oleg BalanovskyVavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Elena LukianovaVavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Nurzhibek KahbatkyzyDepartment of Population Genetics, Institute of General Genetics and Cytology, Science Committee, Ministry of Education and Science of the Republic of Kazakhstan, Almaty, Kazakhstan.
Pavel FlegontovDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic.
Valery ZaporozhchenkoVavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Alexander ImmelDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.
Chuan-Chao WangDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.
Olzhas IxanDepartment of Population Genetics, Institute of General Genetics and Cytology, Science Committee, Ministry of Education and Science of the Republic of Kazakhstan, Almaty, Kazakhstan.
Elmira KhussainovaDepartment of Population Genetics, Institute of General Genetics and Cytology, Science Committee, Ministry of Education and Science of the Republic of Kazakhstan, Almaty, Kazakhstan.
Bakhytzhan BekmanovDepartment of Population Genetics, Institute of General Genetics and Cytology, Science Committee, Ministry of Education and Science of the Republic of Kazakhstan, Almaty, Kazakhstan.
Victor ZaibertInstitute of Archeology and Steppe Civilization, Al-Farabi Kazakh National University, Almaty, Kazakhstan.
Maria LavryashinaKemerovo State Medical University, Kemerovo, Russia.
Elvira PocheshkhovaKuban State Medical University, Krasnodar, Russia.
Yuldash YusupovInstitute of Strategic Research of the Republic of Bashkortostan, Ufa, Russia.
Anastasiya AgdzhoyanVavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Sergey KoshelFaculty of Geography, Lomonosov Moscow State University, Moscow, Russia.ORCID http://orcid.org/0000-0002-4540-2922
Andrei BukinTransbaikal State University, Chita, Russia.
Pagbajabyn NymadawaMongolian Academy of Medical Sciences, Ulaanbaatar, Mongolia.
Shahlo TurdikulovaCenter for Advanced Technologies, Ministry of Innovational Development, Tashkent, Uzbekistan.
Dilbar DalimovaCenter for Advanced Technologies, Ministry of Innovational Development, Tashkent, Uzbekistan.
Mikhail ChurnosovBelgorod State University, Belgorod, Russia.
Roza SkhalyakhoFederal State Budgetary Institution 'Research Centre for Medical Genetics', Moscow, Russia.
Denis DaraganFederal State Budgetary Institution 'Research Centre for Medical Genetics', Moscow, Russia.
Yuri BogunovVavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Anna BogunovaFederal State Budgetary Institution 'Research Centre for Medical Genetics', Moscow, Russia.
Alexandr ShtrunovFederal State Budgetary Institution 'Research Centre for Medical Genetics', Moscow, Russia.
Nadezhda DubovaInstitute of Ethnology and Anthropology, Russian Academy of Sciences, Moscow, Russia.
Maxat ZhabaginNational Laboratory Astana, Nazarbayev University, Astana, Kazakhstan.ORCID http://orcid.org/0000-0003-3414-0610
Levon YepiskoposyanLaboratory of Ethnogenomics, Institute of Molecular Biology, National Academy of Sciences, Yerevan, Armenia.
Vladimir ChurakovUdmurt Institute of History, Language and Literature, Udmurt Federal Research Center, Ural Branch, Russian Academy of Sciences, Izhevsk, Russia.
Nikolay PisleginUdmurt Institute of History, Language and Literature, Udmurt Federal Research Center, Ural Branch, Russian Academy of Sciences, Izhevsk, Russia.
Larissa DambaResearch Institute of Medical and Social Problems and Control, Healthcare Department of Tuva Republic, Kyzyl, Russia.
Ludmila SaroyantsLeprosy Research Institute, Astrakhan, Russia.
Khadizhat DibirovaVavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Lubov AtramentovaV. N. Karazin Kharkiv National University, Kharkiv, Ukraine.
Olga UtevskaV. N. Karazin Kharkiv National University, Kharkiv, Ukraine.
Eldar IdrisovAstrakhan Branch, Russian Presidential Academy of National Economy and Public Administration under the President of the Russian Federation, Astrakhan, Russia.
Evgeniya KamenshchikovaFederal State Budgetary Institution 'Research Centre for Medical Genetics', Moscow, Russia.
Irina EvseevaNorthern State Medical University, Arkhangelsk, Russia.
Mait MetspaluEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia.ORCID http://orcid.org/0000-0003-3099-9161
Alan K OutramDepartment of Archaeology, University of Exeter, Exeter, UK.
Martine RobbeetsEurasia3angle Research Group, Max Planck Institute for the Science of Human History, Jena, Germany.
Leyla DjansugurovaDepartment of Population Genetics, Institute of General Genetics and Cytology, Science Committee, Ministry of Education and Science of the Republic of Kazakhstan, Almaty, Kazakhstan.
Elena BalanovskaFederal State Budgetary Institution 'Research Centre for Medical Genetics', Moscow, Russia.
Stephan SchiffelsDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID http://orcid.org/0000-0002-1017-9150
Wolfgang HaakDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.
David ReichDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Johannes KrauseDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany. krause@shh.mpg.de.ORCID http://orcid.org/0000-0001-9144-3920

Funding

Population mixture in evolutionary and medical geneticsR01GM100233 · NIGMS · HARVARD MEDICAL SCHOOL · PI PATTERSON, NICK J, REICH, DAVID E · 2012 to 2019
$2.7M
European Research Council 646612Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM100233
6 · The paper itself

Abstract

The indigenous populations of inner Eurasia-a huge geographic region covering the central Eurasian steppe and the northern Eurasian taiga and tundra-harbour tremendous diversity in their genes, cultures and languages. In this study, we report novel genome-wide data for 763 individuals from Armenia, Georgia, Kazakhstan, Moldova, Mongolia, Russia, Tajikistan, Ukraine and Uzbekistan. We furthermore report additional damage-reduced genome-wide data of two previously published individuals from the Eneolithic Botai culture in Kazakhstan (~5,400 BP). We find that present-day inner Eurasian populations are structured into three distinct admixture clines stretching between various western and eastern Eurasian ancestries, mirroring geography. The Botai and more recent ancient genomes from Siberia show a decrease in contributions from so-called 'ancient North Eurasian' ancestry over time, which is detectable only in the northern-most 'forest-tundra' cline. The intermediate 'steppe-forest' cline descends from the Late Bronze Age steppe ancestries, while the 'southern steppe' cline further to the south shows a strong West/South Asian influence. Ancient genomes suggest a northward spread of the southern steppe cline in Central Asia during the first millennium BC. Finally, the genetic structure of Caucasus populations highlights a role of the Caucasus Mountains as a barrier to gene flow and suggests a post-Neolithic gene flow into North Caucasus populations from the steppe.

Indexed as

Asian PeopleGene FlowGeographyHumansRussia

Identifiers

PMID31036896
PMCPMC6542712

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