Evidence map›Paper›PMID 31036871›Full record

ArticleScientific reports2019

PulmoBind Imaging Measures Reduction of Vascular Adrenomedullin Receptor Activity with Lack of effect of Sildenafil in Pulmonary Hypertension.

Nassiba Merabet, Mohamed Jalloul Nsaibia, Quang Trinh Nguyen, Yan Fen Shi, Myriam Letourneau, Alain Fournier, Jean-Claude Tardif, François Harel, Jocelyn Dupuis

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Translational studies of adrenomedullin and related peptides regarding cardiovascular diseases.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Nassiba MerabetResearch Center, Montreal Heart Institute, 5000, Belanger, Montreal, QC, H1T 1C8, Canada.
Mohamed Jalloul NsaibiaResearch Center, Montreal Heart Institute, 5000, Belanger, Montreal, QC, H1T 1C8, Canada.
Quang Trinh NguyenResearch Center, Montreal Heart Institute, 5000, Belanger, Montreal, QC, H1T 1C8, Canada.
Yan Fen ShiResearch Center, Montreal Heart Institute, 5000, Belanger, Montreal, QC, H1T 1C8, Canada.
Myriam LetourneauINRS-Institut Armand Frappier, Laval, Québec, Canada.
Alain FournierINRS-Institut Armand Frappier, Laval, Québec, Canada.
Jean-Claude TardifResearch Center, Montreal Heart Institute, 5000, Belanger, Montreal, QC, H1T 1C8, Canada.
François HarelResearch Center, Montreal Heart Institute, 5000, Belanger, Montreal, QC, H1T 1C8, Canada.
Jocelyn DupuisResearch Center, Montreal Heart Institute, 5000, Belanger, Montreal, QC, H1T 1C8, Canada. dupuisj@me.com.
Montreal Heart Institute · CAArmand Frappier Museum · CAInstitut National de la Recherche Scientifique · CAUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial dysfunction is a core pathophysiologic process in pulmonary arterial hypertension (PAH). We developed PulmoBind (PB), a novel imaging biomarker of the pulmonary vascular endothelium.

Indexed as

AdrenomedullinAnimalsBiomarkersEndothelium, VascularHypertension, PulmonaryLungMalePeptide FragmentsPulmonary ArteryRatsReceptors, AdrenomedullinSildenafil CitrateTechnetiumAdrenomedullinadrenomedullin (22-52), glycyl-glycyl-alanyl-glycyl-cysteinyl-(PEG)4-cysteinyl-BiomarkersPeptide FragmentsReceptors, AdrenomedullinSildenafil CitrateTechnetium

Identifiers

PMID31036871
PMCPMC6488585
OpenAlexW2940741653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.