Evidence map›Paper›PMID 31036678›Full record

ArticleG3 (Bethesda, Md.)2019

A Genetic Screen Using the

Rose C Pletcher, Sara L Hardman, Sydney F Intagliata, Rachael L Lawson, Aumunique Page, Jason M Tennessen

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  10. Life science alliance · 2023
    Article
  11. Article
  12. Hyperpolarized mitochondria accumulate inJournal of cell science · 2020
    Article
  13. Article
  14. Article
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rose C PletcherDepartment of Biology, Indiana University, 1001 East Third Street, Bloomington, IN 47405.
Sara L HardmanDepartment of Biology, Indiana University, 1001 East Third Street, Bloomington, IN 47405.
Sydney F IntagliataDepartment of Biology, Indiana University, 1001 East Third Street, Bloomington, IN 47405.
Rachael L LawsonDepartment of Biology, Indiana University, 1001 East Third Street, Bloomington, IN 47405.
Aumunique PageDepartment of Biology, Indiana University, 1001 East Third Street, Bloomington, IN 47405.
Jason M TennessenDepartment of Biology, Indiana University, 1001 East Third Street, Bloomington, IN 47405 jtenness@indiana.edu.ORCID 0000-0002-3527-5683
Indiana University Bloomington · US

Funding

Resource Project CoreU41HG000739 · NHGRI · HARVARD UNIVERSITY · PI PERRIMON, NORBERT · 2014 to 2022
$32.3M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
A Drosophila Model for the Regulation of Aerobic GlycolysisR35GM119557 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Jason Michael Tennessen · 2016 to 2026
$4.7M
NHGRI NIH HHS U41 HG000739NIGMS NIH HHS R01 GM084947NIGMS NIH HHS R35 GM119557NIH HHS P40 OD018537
6 · The paper itself

Abstract

The metabolic enzymes that compose glycolysis, the citric acid cycle, and other pathways within central carbon metabolism have emerged as key regulators of animal development. These enzymes not only generate the energy and biosynthetic precursors required to support cell proliferation and differentiation, but also moonlight as regulators of transcription, translation, and signal transduction. Many of the genes associated with animal metabolism, however, have never been analyzed in a developmental context, thus highlighting how little is known about the intersection of metabolism and development. Here we address this deficiency by using the

Indexed as

Gene Expression Regulation, DevelopmentalGene Expression Regulation, EnzymologicRNA InterferenceAnimalsCrosses, GeneticDrosophila melanogasterDrosophila ProteinsEyeOrganogenesisPhenotypeDrosophila ProteinsDrosophilaglutamine metabolismmetabolismmitochondriaoxidative phosphorylation

Identifiers

PMID31036678
PMCPMC6643872
OpenAlexW2953260789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.