ArticleProceedings of the National Academy of Sciences of the United States of America2019
Responses in area hMT+ reflect tuning for both auditory frequency and motion after blindness early in life.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neural substrates of spatial processing and navigation in blindness: An activation likelihood estimation meta-analysis.Frontiers in neuroscience · 2022Pooled it
- Aligned representation of visual and tactile motion directions in hMT+/V5 and fronto-parietal regions.Nature communications · 2026Article
- Pathways of Cross-Modal Access to the Visual Cortex in Late Blindness.Research square · 2026Article
- Sensory abnormalities in autism spectrum disorder and their in vitro modeling.Translational psychiatry · 2025Review
- Stimulus-responsive and task-dependent activations in occipital regions during pitch perception by early blind listeners.Human brain mapping · 2024Article
- Project Prakash: Merging Basic Science and Societal Service in Vision Research.Policy insights from the behavioral and brain sciences · 2023Article
- Visual cortex responds to sound onset and offset during passive listening.Journal of neurophysiology · 2022Article
- Learning to see after early and extended blindness: A scoping review.Frontiers in psychology · 2022Article
- The Effect of Congenital and Acquired Bilateral Anophthalmia on Brain Structure.Neuro-ophthalmology (Aeolus Press) · 2021Article
- New insights into cortical development and plasticity: from molecules to behavior.Current opinion in physiology · 2020Article
- Article
- Increased Right Posterior STS Recruitment Without Enhanced Directional-Tuning During Tactile Motion Processing in Early Deaf Individuals.Frontiers in neuroscience · 2020Article
- Early Blindness Shapes Cortical Representations of Auditory Frequency within Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
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3 authors.
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Abstract
Previous studies report that human middle temporal complex (hMT+) is sensitive to auditory motion in early-blind individuals. Here, we show that hMT+ also develops selectivity for auditory frequency after early blindness, and that this selectivity is maintained after sight recovery in adulthood. Frequency selectivity was assessed using both moving band-pass and stationary pure-tone stimuli. As expected, within primary auditory cortex, both moving and stationary stimuli successfully elicited frequency-selective responses, organized in a tonotopic map, for all subjects. In early-blind and sight-recovery subjects, we saw evidence for frequency selectivity within hMT+ for the auditory stimulus that contained motion. We did not find frequency-tuned responses within hMT+ when using the stationary stimulus in either early-blind or sight-recovery subjects. We saw no evidence for auditory frequency selectivity in hMT+ in sighted subjects using either stimulus. Thus, after early blindness, hMT+ can exhibit selectivity for auditory frequency. Remarkably, this auditory frequency tuning persists in two adult sight-recovery subjects, showing that, in these subjects, auditory frequency-tuned responses can coexist with visually driven responses in hMT+.
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