Evidence map›Paper›PMID 31036602›Full record

ArticleInfection and immunity2019

The HIF-1α/LC3-II Axis Impacts Fungal Immunity in Human Macrophages.

Dirk Friedrich, Dorinja Zapf, Björn Lohse, Roger A Fecher, George S Deepe, Jan Rupp

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Dirk Friedrich *Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.ORCID 0000-0001-8812-489X
Dorinja Zapf *Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.
Björn LohseDepartment of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.
Roger A FecherDivision of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
George S Deepe *Division of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Jan Rupp *Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany jan.rupp@uksh.de.ORCID 0000-0001-8722-1233
University of Lübeck · DECincinnati Children's Hospital Medical Center · USGerman Center for Infection Research · DEUniversity of Cincinnati Medical Center · US

Funding

GM-CSF-Induced Metal Sequestration and HistoplasmaR01AI106269 · NIAID · UNIVERSITY OF CINCINNATI · PI DEEPE, GEORGE S. · 2013 to 2022
$5.0M
HIF Regulation of Histoplasma PathogenesisR01AI133797 · NIAID · UNIVERSITY OF CINCINNATI · PI DEEPE, GEORGE S. · 2018 to 2022
$2.0M
NIAID NIH HHS R01 AI106269NIAID NIH HHS R01 AI133797
6 · The paper itself

Abstract

The fungal pathogen

Indexed as

AnimalsAutophagyHistoplasmaHistoplasmosisHumansHypoxia-Inducible Factor 1, alpha SubunitMacrophagesMaleMiceMicrotubule-Associated ProteinsPhagosomesHypoxia-Inducible Factor 1, alpha SubunitMAP1LC3B protein, humanMicrotubule-Associated Proteinsautophagyfungal immunityHIF-1Histoplasma capsulatumLC3macrophages

Identifiers

PMID31036602
PMCPMC6589057
OpenAlexW2941182103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.