ArticleJournal of neurointerventional surgery2019
High frequency optical coherence tomography assessment of homogenous neck coverage by intrasaccular devices predicts successful aneurysm occlusion.
Article in Journal of neurointerventional surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Imaging of intracranial aneurysms in animals: a systematic review of modalities.Neurosurgical review · 2023Pooled it
- From intravascular imaging to adaptive vascular care: intelligent photonics and digital twins in panvascular disease.Light, science & applications · 2026Review
- Feasibility of Using Angioscopy to Visualize the Internal Vessel Wall of the Internal Carotid Artery.Clinical neuroradiology · 2026Article
- Advancements in Brain Aneurysm Management: Integrating Neuroanatomy, Physiopathology, and Neurosurgical Techniques.Medicina (Kaunas, Lithuania) · 2024Review
- Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe.Science translational medicine · 2024Article
- Optical Coherence Tomography in Cerebrovascular Disease: Open up New Horizons.Translational stroke research · 2023Review
- Treatment of experimental aneurysms with a GPX embolic agent prototype: preliminary angiographic and histological results.Journal of neurointerventional surgery · 2022Article
- Imaging Modalities for Intracranial Aneurysm: More Than Meets the Eye.Frontiers in cardiovascular medicine · 2022Review
- High-resolution image-guided WEB aneurysm embolization by high-frequency optical coherence tomography.Journal of neurointerventional surgery · 2021Article
- Adaptive Remodeling in the Elastase-induced Rabbit Aneurysms.Experimental mechanics · 2021Article
- Applications of a Novel Microangioscope for Neuroendovascular Intervention.AJNR. American journal of neuroradiology · 2021Article
- Longitudinal Monitoring of Flow-Diverting Stent Tissue Coverage After Implant in a Bifurcation Model Using Neurovascular High-Frequency Optical Coherence Tomography.Neurosurgery · 2020Article
- A neurovascular high-frequency optical coherence tomography system enables in situ cerebrovascular volumetric microscopy.Nature communications · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundHigh frequency optical coherence tomography (HF-OCT) is a novel intravascular imaging technology developed for use in the cerebral vasculature. We hypothesize that HF-OCT characterization of intrasaccular device neck coverage can prognosticate exclusion of the aneurysm from the circulation.
methodsBifurcation and sidewall aneurysms were made in six dogs. Seven aneurysms were treated with next generation intrasaccular devices (NGID) and four with traditional platinum coils. HF-OCT was performed to interrogate gaps in the neck coverage, coil herniation, or acute thrombus formation. Animals were re-imaged at 7, 30, 90, and 180 days following aneurysm embolization. An automated image processing method segmented the devices at the neck of the aneurysm and quantified neck coverage. The largest coverage gap was used to predict aneurysm occlusion at 180 days.
resultsNo difference was found in occlusion rates between the coil and NGID groups (P=0.45). Successful segmentation of the NGID construct was achieved in all cases. A coverage gap >1 mm
conclusionsHF-OCT enables precise and accurate measurement of coverage gaps at the neck of aneurysms treated with intrasaccular devices in vivo. We provide in vivo evidence that uniform aneurysm neck coverage by intrasaccular devices is critical for aneurysm occlusion.
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