Evidence map›Paper›PMID 31036548›Full record

ArticleDevelopment (Cambridge, England)2019

Wnt signaling mediates new nephron formation during zebrafish kidney regeneration.

Caramai N Kamei, Thomas F Gallegos, Yan Liu, Neil Hukriede, Iain A Drummond

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 49 citations in OpenAlex.

  1. Mesenchymal-derived neural progenitors underlie localbioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Chronic exposure to low levels of glyphosate and metals induces kidney dysfunction.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Epithelial tubule interconnection driven by HGF-Met signaling in the kidney.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. In Vivo Assessment of Laboratory-Grown Kidney Tissue Grafts.Bioengineering (Basel, Switzerland) · 2023
    Article
  15. Principles of Zebrafish Nephron Segment Development.Journal of developmental biology · 2023
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Caramai N KameiMassachusetts General Hospital, Department of Medicine, Nephrology Division, 149 13th Street, Charlestown, MA 02129, USA.
Thomas F GallegosMassachusetts General Hospital, Department of Medicine, Nephrology Division, 149 13th Street, Charlestown, MA 02129, USA.
Yan LiuMassachusetts General Hospital, Department of Medicine, Nephrology Division, 149 13th Street, Charlestown, MA 02129, USA.
Neil HukriedeDepartment of Developmental Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA.
Iain A DrummondMassachusetts General Hospital, Department of Medicine, Nephrology Division, 149 13th Street, Charlestown, MA 02129, USA idrummond@mgh.harvard.edu.ORCID 0000-0003-3734-1231
Massachusetts General Hospital · USHarvard University · USUniversity of Pittsburgh · US

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
Regulation of Renal Progenitor Cells in Regenerating KidneysR01DK069403 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HUKRIEDE, NEIL A · 2006 to 2020
$4.8M
Mechanisms of tubule interconnectionUH3DK107372 · NIDDK · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI DRUMMOND, IAIN A. · 2017 to 2019
$1.3M
Mechanisms of tubule interconnectionUH2DK107372 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI DRUMMOND, IAIN A. · 2015 to 2016
$725k
Smoking Cessation Intervention with Building Trade UnionR01DP000097 · DP · DANA-FARBER CANCER INSTITUTE · PI BARBEAU, ELIZABETH M · 2004 to 2006
$497k
NCCDPHP CDC HHS R01 DP000097NIDDK NIH HHS P30 DK079307NIDDK NIH HHS R01 DK069403NIDDK NIH HHS UH2 DK107372NIDDK NIH HHS UH3 DK107372
6 · The paper itself

Abstract

Zebrafish kidneys use resident kidney stem cells to replace damaged tubules with new nephrons: the filtration units of the kidney. What stimulates kidney progenitor cells to form new nephrons is not known. Here, we show that

Indexed as

AnimalsFrizzled ReceptorsKidneyNephronsRegenerationWnt Signaling PathwayZebrafishZebrafish ProteinsFrizzled ReceptorsZebrafish ProteinsAdult organ stem cellFrizzledKidneyNephronRegenerationWnt

Identifiers

PMID31036548
PMCPMC6503981
OpenAlexW2942671315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.