ArticleLangmuir : the ACS journal of surfaces and colloids2019
Design Principles for Thermoresponsive Core-Shell Nanoparticles: Controlling Thermal Transitions by Brush Morphology.
Article in Langmuir : the ACS journal of surfaces and colloids, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Soy protein isolate-pectin fromFood chemistry: X · 2026Article
- Tuning the Cloud-Point and Flocculation Temperature of Poly(2-(diethylamino)ethyl methacrylate)-Based Nanoparticles via a Postpolymerization Betainization Approach.ACS polymers Au · 2021Article
- Thermoresponsive Nanoparticles with Cyclic-Polymer-Grafted Shells Are More Stable than with Linear-Polymer-Grafted Shells: Effect of Polymer Topology, Molecular Weight, and Core Size.The journal of physical chemistry. B · 2021Article
- Synthesis of a thermoresponsive crosslinked MEOScientific reports · 2021Article
- Theoretical and Experimental Design of Heavy Metal-Mopping Magnetic Nanoparticles.ACS applied materials & interfaces · 2021Article
- Constrained thermoresponsive polymers - new insights into fundamentals and applications.Beilstein journal of organic chemistry · 2021Review
- From Single-Core Nanoparticles in Ferrofluids to Multi-Core Magnetic Nanocomposites: Assembly Strategies, Structure, and Magnetic Behavior.Nanomaterials (Basel, Switzerland) · 2020Review
- Thermoresponsive, hollow, degradable core-shell nanoparticles for intra-articular delivery of anti-inflammatory peptide.Journal of controlled release : official journal of the Controlled Release Society · 2020Article
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Authors and funding
3 authors.
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Abstract
In this feature article, we summarize our recent work on understanding and controlling the thermal behavior of nanoparticles grafted with thermoresponsive polymer shells. Precision synthesis of monodisperse superparamagnetic iron oxide nanocrystals was combined with irreversible dense grafting of nitrodopamide-anchored thermoresponsive polymer chains. We provide an overview of how the dense and stable grafting of biomedically relevant polymers, including poly(ethylene glycol), poly( N-isopropylacrylamide), polysarcosin, and polyoxazolines, can be achieved. This platform has made it possible for us to demonstrate that the polymer brush geometry, as defined by the nanoparticle core and relative polymer brush size, determines the thermal transitions of the polymer brush. We furthermore summarize our work on how the polymer shell transitions and nanoparticle aggregation can be tuned. With the independent variation of the core and the shell, we can optimize and precisely control the thermally controlled solubility of our system. Finally, our feature article gives examples relevant to current and future applications. We show how the thermal response of the shell influences the nanoparticle performance in biological fluids and interactions with proteins and cells, also under purely magnetic actuation of the nanoparticles through the superparamagnetic iron oxide core.
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Registered trials
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