Evidence map›Paper›PMID 31035642›Full record

ArticleViruses2019

Epidemiological, Molecular, and Clinical Features of Norovirus Infections among Pediatric Patients in Qatar.

Shilu Mathew, Khalid Alansari, Maria K Smatti, Hassan Zaraket, Asmaa A Al Thani, Hadi M Yassine

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Characteristics of GII.4 Norovirus Versus Other Genotypes in Sporadic Pediatric Infections in Davidson County, Tennessee, USA.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Shilu MathewBiomedical Research Center, Qatar University, Doha 2713, Qatar. shilu.mathew@qu.edu.qa.
Khalid AlansariPediatric Emergency Center, Hamad Medical Corporation, Doha 3050, Qatar. dkmaa@hotmail.com.
Maria K SmattiBiomedical Research Center, Qatar University, Doha 2713, Qatar. msmatti@qu.edu.qa.ORCID 0000-0002-7621-0130
Hassan ZaraketDepartment of Experimental Pathology, Microbiology, and Immunology, Faculty of Medicine, American University of Beirut, Beirut 1107 2020, Lebanon. hz34@aub.edu.lb.ORCID 0000-0003-3807-6409
Asmaa A Al ThaniBiomedical Research Center, Qatar University, Doha 2713, Qatar. aaja@qu.edu.qa.
Hadi M YassineBiomedical Research Center, Qatar University, Doha 2713, Qatar. hyassine@qu.edu.qa.ORCID 0000-0001-7592-2788
Qatar University · QAAmerican University of Beirut · LBHamad Medical Corporation · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNorovirus (NoV) is recognized as the second most important etiological agent leading to acute gastroenteritis globally. In order to determine the burden and characteristics of NoV infections in children in Qatar, profiling of circulating genotypes and their correlation with demographics and clinical manifestations were evaluated.

methodsA total of 177 NoV-positive fecal samples were collected from children suffering from acute gastroenteritis (AGE) during two-year period between June 2016 and June 2018. The age of the subjects ranged between 3 months and 12 years (median of 15 months). Genotyping was performed by amplifying and sequencing parts of viral VP1 and RNA-dependent RNA polymerase (RdRp) regions. Phylogenetic analysis and evolutionary relationships were performed using MEGA7.0. Fisher's exact test was used to run statistical analysis for the clinical and demographical characteristics of circulating strains.

resultsOverall, NoV infections were relatively higher in males than females with a ratio of 1.3:1 (

conclusionThis is the first report about NoV molecular epidemiology in Qatar. The most detected NoV strain was genogroup GII, which is the dominant genotype in the Middle East region. Further, we report GII.4, GII.2, and GII.3 as the most predominant NoV genotypes in our study. Moreover, disease severity scores were higher among children genotyped with genogroup GI (GI.4) and genogroup GII (GII.4, GII.2, GII.3, GII.6, and GII.7).

Indexed as

Age FactorsCaliciviridae InfectionsChildChild, PreschoolFemaleGenetic VariationGenotypeHumansIncidenceInfantMaleMolecular EpidemiologyNorovirusPublic Health SurveillanceQatarSeasonsage-specificgenotypingnorovirusseverity

Identifiers

PMID31035642
PMCPMC6563317
OpenAlexW2943727180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.