ArticleTropical medicine and infectious disease2019
High Endemicity of Soil-Transmitted Helminths in a Population Frequently Exposed to Albendazole but No Evidence of Antiparasitic Resistance.
Article in Tropical medicine and infectious disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- Genetic diversity, population structure, and benzimidazole resistance profiling of Ascaris lumbricoides in northwestern Thailand.Parasitology research · 2026Article
- Heavy burden of soil-transmitted helminth infections in a remote and impoverished indigenous community of Honduras revealed by real time polymerase chain reaction.Infectious diseases of poverty · 2026Article
- A decade of health research capacity building in Honduras: institutional transformation, challenges, and lessons learned.Global health action · 2025Article
- Prevalence and Risk Factors of Soil-Transmitted Helminths Among Students in Fogera District, Northwest Ethiopia.Global health, epidemiology and genomics · 2025Article
- Factors associated with hookworm and Schistosoma mansoni infections among school-aged children in Mayuge district, Uganda.BMC public health · 2024Article
- Anthelmintic resistance in soil-transmitted helminths: One-Health considerations.Parasitology research · 2023Review
- Present status with impacts and roles of miRNA on Soil Transmitted Helminthiosis control: A review.Current research in pharmacology and drug discovery · 2023Review
- Population genomics of ancient and modern Trichuris trichiura.Nature communications · 2022Article
- Improving stool sample processing and pyrosequencing for quantifying benzimidazole resistance alleles in Trichuris trichiura and Necator americanus pooled eggs.Parasites & vectors · 2021Article
- Characterization of the β-tubulin gene family in Ascaris lumbricoides and Ascaris suum and its implication for the molecular detection of benzimidazole resistance.PLoS neglected tropical diseases · 2021Article
- An inactivated bacterium (paraprobiotic) expressingOne health (Amsterdam, Netherlands) · 2021Article
- First Molecular Characterization ofPathogens (Basel, Switzerland) · 2021Article
- What Will Happen to Biomedical Research in Low-and-Middle Income Countries in the PostCOVID-19 World?Current tropical medicine reports · 2021Review
- Expanding detection windows for discriminating single nucleotide variants using rationally designed DNA equalizer probes.Nature communications · 2020Article
- An Integrated Study ofTropical medicine and infectious disease · 2020Article
- Anthelmintic drug discovery: target identification, screening methods and the role of open science.Beilstein journal of organic chemistry · 2020Review
- Soil-Transmitted Helminth Vaccines: Are We Getting Closer?Frontiers in immunology · 2020Review
- Absence of mutations associated with resistance to benzimidazole in the beta-tubulin gene of Ascaris suum.Revista da Sociedade Brasileira de Medicina Tropical · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
introductionSoil-transmitted helminths (STHs) are gastrointestinal parasites widely distributed in tropical and subtropical areas. Mass drug administration (MDA) of benzimidazoles (BZ) is the most recommended for STH control. These drugs have demonstrated limited efficacy against
methodsA parasitological survey was performed as part of this study, the Kato-Katz technique was used to determine STH prevalence in children of La Hicaca, Honduras. A subgroup of children received anthelminthic treatment in order to recover adult parasite specimens that were analyzed through molecular biology techniques. Genetic regions containing codons 200, 198, and 167 of the -tubulin gene of
resultsStool samples were collected from 106 children. The overall STH prevalence was 75.47%, whereby
conclusionAlthough the inability to find single-nucleotide polymorphisms (SNPs) in the small sample analyzed for the present report does not exclude the possibility of their occurrence, these results suggest that, at present, Honduras's challenges in STH control may not be related to drug resistance but to environmental conditions and/or host factors permitting reinfections.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.