Evidence map›Paper›PMID 31035590›Full record

ArticleInternational journal of molecular sciences2019

rs4143815-

Chiara Zanusso, Eva Dreussi, Roberto Bortolus, Chiara Romualdi, Sara Gagno, Elena De Mattia, Loredana Romanato, Franca Sartor, Luca Quartuccio, Erika Cecchin and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. The roles of PD-1/PD-L1 in the prognosis and immunotherapy of prostate cancer.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Chiara ZanussoExperimental and Clinical Pharmacology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy. czanusso@cro.it.
Eva DreussiExperimental and Clinical Pharmacology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy. edreussi@cro.it.
Roberto BortolusDepartment of Radiation Oncology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy. rbortolus@cro.it.
Chiara RomualdiDepartment of Biology, University of Padova, 35122 Padova, Italy. chiara.romualdi@unipd.it.ORCID 0000-0003-4792-9047
Sara GagnoExperimental and Clinical Pharmacology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy. sgagno@cro.it.
Elena De MattiaExperimental and Clinical Pharmacology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy. edemattia@cro.it.ORCID 0000-0003-4948-8767
Loredana RomanatoExperimental and Clinical Pharmacology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy. lromanato@cro.it.
Franca SartorExperimental and Clinical Pharmacology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy. fsartor@cro.it.
Luca QuartuccioRheumatology Clinic, Department of Medical and Biological Sciences, University Hospital "Santa Maria della Misericordia", 33100 Udine, Italy. luca.quartuccio@asuiud.sanita.fvg.it.
Erika CecchinExperimental and Clinical Pharmacology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy. ececchin@cro.it.ORCID 0000-0001-7517-7490
Giuseppe ToffoliExperimental and Clinical Pharmacology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy. gtoffoli@cro.it.ORCID 0000-0002-5323-4762
Centro di Riferimento Oncologico · ITOspedale Santa Maria della Misericordia di Udine · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Up to 30-50% of patients with locally advanced prostate cancer (PCa) undergoing radiotherapy (RT) experience biochemical recurrence (BCR). The immune system affects the RT response. Immunogenetics could define new biomarkers for personalization of PCa patients' treatment. The aim of this study is to define the immunogenetic biomarkers of 10 year BCR (primary aim), 10 year overall survival (OS) and 5 year BCR (secondary aims). In this mono-institutional retrospective study, 549 Caucasian patients (a discovery set

Indexed as

Biomarkers, TumorAgedB7-H1 AntigenCombined Modality TherapyGenotypeHumansImmunogeneticsKaplan-Meier EstimateMaleMiddle AgedNeoplasm GradingNeoplasm StagingPolymorphism, Single NucleotidePrognosisProportional Hazards ModelsProstatic NeoplasmsB7-H1 AntigenBiomarkers, TumorCD274 protein, humanbiochemical recurrencebiomarkerimmunogeneticsprostate cancerradiotherapy

Identifiers

PMID31035590
PMCPMC6539607
OpenAlexW2940751310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.