Evidence map›Paper›PMID 31035491›Full record

ReviewCells2019

Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?

Moritz J Strowitzki, Eoin P Cummins, Cormac T Taylor

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 2 pooled it
8.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 2 syntheses or guidelines pooled it, 233 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Context-dependent variability of HIF heterodimers influences interactions with macromolecular and small molecule partners.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Ipriflavone FromMedComm · 2026
    Article
  11. Article
  12. Review
  13. Enhancing the efficacy of VEGF inhibitors by co-inhibition of HIF in the treatment of glioblastoma.Apoptosis : an international journal on programmed cell death · 2026
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Moritz J StrowitzkiUCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Moritz.strowitzki@ucd.ie.ORCID 0000-0001-6967-9283
Eoin P CumminsUCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. eoin.cummins@ucd.ie.ORCID 0000-0002-9346-8299
Cormac T TaylorUCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. cormac.taylor@ucd.ie.
University College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All metazoans that utilize molecular oxygen (O

Indexed as

AnimalsHumansHydroxylationHypoxiaHypoxia-Inducible Factor 1, alpha SubunitHypoxia-Inducible Factor-Proline DioxygenasesMixed Function OxygenasesProlyl-Hydroxylase InhibitorsHypoxia-Inducible Factor 1, alpha SubunitHypoxia-Inducible Factor-Proline DioxygenasesMixed Function OxygenasesProlyl-Hydroxylase InhibitorsCep192factor inhibiting HIFFOXO3aHIF-prolyl hydroxylaseshypoxiahypoxia-inducible factorIKK-βMAPK6mass spectrometryOTUB1p105p53prolyl hydroxylationRIPK4

Identifiers

PMID31035491
PMCPMC6562979
OpenAlexW2940577902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.