Evidence map›Paper›PMID 31035465›Full record

ArticleNutrients2019

A Review of Dietary Therapy for IBD and a Vision for the Future.

Nicole Green, Talya Miller, David Suskind, Dale Lee

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. Pooled it
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  10. Nutraceuticals and biotics in pediatric gastrointestinal disorders.European journal of clinical nutrition · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicole GreenDepartment of Pediatric Gastroenterology and Hepatology, Seattle Children's Hospital, Seattle, WA 98105, USA. nicole.green@seattlechildrens.org.
Talya MillerDepartment of Pediatric Gastroenterology and Hepatology, Seattle Children's Hospital, Seattle, WA 98105, USA. talya.miller@seattlechildrens.org.ORCID 0000-0001-8361-9471
David SuskindDepartment of Pediatric Gastroenterology and Hepatology, Seattle Children's Hospital, Seattle, WA 98105, USA. david.suskind@seattlechildrens.org.
Dale LeeDepartment of Pediatric Gastroenterology and Hepatology, Seattle Children's Hospital, Seattle, WA 98105, USA. dale.lee@seattlechildrens.org.
Seattle Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a chronic inflammatory condition affecting the gastrointestinal tract. The rising incidence of IBD has been associated with urbanization and shifts toward a Westernized diet. The intestinal microbiome has been a focus of disease pathogenesis and also therapeutic intervention. Dietary therapy for IBD has been well-studied with exclusive enteral nutrition, a formula-based diet with the exclusion of foods. In addition, interest in food-based exclusion diets has been increasing, with patients and families leading the charge. Challenges with dietary therapy for IBD include the lack of understanding of a detailed mechanistic pathway to explain the impact of diet on IBD pathogenesis and the difficult nature of designing and implementing dietary clinical trials. Epidemiological studies have demonstrated associations and intervention studies have demonstrated efficacy, but specific dietary targets remain as hypotheses at present. Current IBD therapy focuses on suppression of the immune system, yet the incomplete efficacy of present drugs suggests that other therapies must be developed and employed. Dietary interventions, with known ability to modulate the intestinal microbiome, are a unique opportunity to improve outcomes in IBD. Dietary intervention trials are challenging, and capturing both broad dietary patterns as well as exposure to individual food compounds is important. With increasing patient interest and preliminary research in dietary therapy indicating efficacy, it is imperative to further advance the science of utilizing diet in IBD, as well as to support patients by proactively addressing diet within their care plan.

Indexed as

Anti-Inflammatory AgentsDietGastrointestinal MicrobiomeHumansInflammatory Bowel DiseasesAnti-Inflammatory AgentsCrohndietexclusive enteral nutritioninflammatory bowel diseasenutritionulcerative colitis

Identifiers

PMID31035465
PMCPMC6566428
OpenAlexW2940855170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.