Evidence map›Paper›PMID 31034622›Full record

ArticleAlcoholism, clinical and experimental research2019

Genes, Roommates, and Residence Halls: A Multidimensional Study of the Role of Peer Drinking on College Students' Alcohol Use.

Rebecca L Smith, Jessica E Salvatore, Fazil Aliev, Zoe Neale, Peter Barr, Spit for Science Working Group, Danielle M Dick

Abstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Rebecca L SmithDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia.ORCID 0000-0002-0874-4616
Jessica E SalvatoreDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia.ORCID 0000-0001-5504-5087
Fazil AlievDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia.
Zoe NealeDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia.ORCID 0000-0001-6440-2445
Peter BarrDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia.
Spit for Science Working Group
Danielle M DickDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia.ORCID 0000-0002-1636-893X

Funding

Project 5 - Genetic architecture of alcohol use disorder using cross-trait genetic correlations and public next-generation sequencing studiesP50AA022537 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI JENNIFER T WOLSTENHOLME · 2014 to 2026
$19.6M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR031990 · NCRR · VIRGINIA COMMONWEALTH UNIVERSITY · PI CLORE, JOHN N. · 2010 to 2011
$7.7M
An Alcohol Affected Sib Pair Study of Alcohol DependenceR37AA011408 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENDLER, KENNETH SEEDMAN · 2007 to 2016
$6.5M
Twin, molecular, and developmental approaches to understanding alcohol misuseK02AA018755 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DICK, DANIELLE M · 2010 to 2019
$1.3M
Genetics, Romantic Relationships, and Alcohol Misuse in Emerging AdulthoodK01AA024152 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI SALVATORE, JESSICA E · 2016 to 2020
$741k
Leveraging sources of heterogeneity to delineate the genetic architecture of major depressive disorderK01MH113848 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI PETERSON, ROSEANN ELIZABETH · 2018 to 2020
$546k
The moderating effect of genetic predispositions on alcohol intervention outcomes in youthF31AA027130 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI NEALE, ZOE ELIZABETH · 2018 to 2019
$72k
NCRR NIH HHS UL1 RR031990NIAAA NIH HHS F31 AA027130NIAAA NIH HHS K01 AA024152NIAAA NIH HHS K02 AA018755NIAAA NIH HHS P20 AA107828NIAAA NIH HHS P50 AA022537NIAAA NIH HHS R37 AA011408NIMH NIH HHS K01 MH113848
6 · The paper itself

Abstract

backgroundPeer drinking is one of the most robust predictors of college students' alcohol use and can moderate students' genetic risk for alcohol use. Peer effect research generally suffers from 2 problems: selection into peer groups and relying more on perceptions of peer alcohol use than peers' self-report. The goal of the present study was to overcome those limitations by capitalizing on a genetically informed sample of randomly assigned college roommates to examine multiple dimensions of peer influence and the interplay between peer effects and genetic predisposition on alcohol use, in the form of polygenic scores.

methodsWe used a subsample (n = 755) of participants from a university-wide, longitudinal study at a large, diverse, urban university. Participants reported their own alcohol use during fall and spring and their perceptions of college peers' alcohol use in spring. We matched individuals into their rooms and residence halls to create a composite score of peer-reported alcohol use for each of those levels. We examined multiple dimensions of peer influence and whether peer influence moderated genetic predisposition to predict college students' alcohol use using multilevel models to account for clustering at the room and residence hall level.

resultsWe found that polygenic scores (β = 0.12), perceptions of peer drinking (β = 0.37), and roommates' self-reported drinking (β = 0.10) predicted alcohol use (all ps < 0.001), while average alcohol use across residence hall did not (β = -0.01, p = 0.86). We found no evidence for interactions between peer influence and genome-wide polygenic scores for alcohol use.

conclusionsOur findings underscore the importance of genetic predisposition on individual alcohol use and support the potentially causal nature of the association between peer influence and alcohol use.

Indexed as

Peer GroupAlcohol DrinkingAlcohol Drinking in CollegeCohort StudiesFemaleGene-Environment InteractionHousingHumansMaleStudentsYoung AdultAlcoholCollege StudentsGene-Environment InteractionGenetic PredispositionPeer Drinking

Identifiers

PMID31034622
PMCPMC6561118

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.