Evidence map›Paper›PMID 31034592›Full record

ReviewJournal of the American Geriatrics Society2019

Expanding Therapeutic Options for Older Adults: Case-Based Updates in Breast and Lung Cancer.

Allison Magnuson, Rawad Elias, Thuy Koll

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in Journal of the American Geriatrics Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Allison MagnusonDepartment of Medicine, Divisions of Medical Oncology and Geriatrics, University of Rochester Medical Center, Rochester, New York.
Rawad EliasDepartment of Medical Oncology, Hartford HealthCare Cancer Institute, Hartford, Connecticut.
Thuy KollDepartment of Internal Medicine, Division of Geriatrics, Gerontology and Palliative Care Medicine, University of Nebraska, Omaha, Nebraska.
Hartford Hospital · USUniversity of Nebraska at Omaha · USUniversity of Rochester Medical Center · US

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Mitigating Cancer-Related Cognitive Dysfunction in Older Adults with Breast CancerK76AG064394 · NIA · UNIVERSITY OF ROCHESTER · PI MAGNUSON, ALLISON MARIAN · 2019 to 2023
$1.3M
An Expanded Framework to Measure Cognitive Function in Older Adults Undergoing Hematopoietic Cell TransplantationR03AG060095 · NIA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KOLL, THUY · 2019 to 2020
$229k
NCI NIH HHS UG1 CA189961NIA NIH HHS K76 AG064394NIA NIH HHS R03 AG060095
6 · The paper itself

Abstract

Oncology care has become increasingly complex, with a dramatic increase in the number of available therapy options. Many newly developed medications have novel mechanisms of action and include targeted therapies and immunotherapy options. These agents typically have unique side effects that differ from more traditional cytotoxic chemotherapy regimens. Older adults represent the majority of patients with cancer and it is important for geriatricians and primary care providers for older adults to have a general understanding of newer agents and novel therapies, in order to aid in decision-making and supportive care strategies during oncology treatment. This review provides a case-based approach to discussing emerging therapeutic treatment options, including targeted therapies and immune-based therapies, in two common malignancies affecting older adults. Incorporation of available evidence of specific novel therapies in older adult populations is discussed. J Am Geriatr Soc 67:1012-1019, 2019.

Indexed as

Breast NeoplasmsDecision MakingGeriatric AssessmentLung NeoplasmsPatient Education as TopicAgedCombined Modality TherapyFemaleHumanscancer therapycase-based reviewgeriatric oncology

Identifiers

PMID31034592
PMCPMC12447478
OpenAlexW2943178233

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.