Trial reportJournal of the American Geriatrics Society2019
Effects of a Home-based Exercise Program on Anxiety and Mood Disturbances in Older Adults with Cancer Receiving Chemotherapy.
Trial report in Journal of the American Geriatrics Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04035499 (A Mobile Health Exercise Intervention for Older Patients With Myeloid Neoplasms), which is not on this map. Cited by 34 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Mobile Health Exercise Intervention for Older Patients With Myeloid Neoplasms
Who cites it
34 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Comparative efficacy of different exercise interventions for improving quality of life, depression, and anxiety in older adults with cancer: a systematic review and network meta-analysis.BMC geriatrics · 2026Pooled it
- Effects of Exercise on Depression and Anxiety in Breast Cancer Survivors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Cancer medicine · 2025Pooled it
- Exercise Interventions for Depression, Anxiety, and Quality of Life in Older Adults With Cancer: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- Influence of physical exercise on health improvement in older adult cancer patients: a systematic review.Frontiers in public health · 2025Pooled it
- Effects of resistance training on quality of life, fatigue, physical function, and muscular strength during chemotherapy treatment: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Physical activity and nutrition interventions for older adults with cancer: a systematic review.Journal of cancer survivorship : research and practice · 2020Pooled it
- Staying Physically Active During the Quarantine and Self-Isolation Period for Controlling and Mitigating the COVID-19 Pandemic: A Systematic Overview of the Literature.Frontiers in psychology · 2020Pooled it
- Trial
- Effects of Exercise on Cognitive Impairment in Patients Receiving Chemotherapy: A Multicenter Phase III Randomized Controlled Trial.Journal of the National Comprehensive Cancer Network : JNCCN · 2026Trial
- Changes in muscle performance among older adults with myeloid malignancies engaging in a mobile health (mHealth) exercise intervention: a single arm pilot study.BMC geriatrics · 2025Trial
- Exercise and epigenetic ages in older adults with myeloid malignancies.European journal of medical research · 2023Trial
- A single-arm pilot study of a mobile health exercise intervention (GO-EXCAP) in older patients with myeloid neoplasms.Blood advances · 2022Trial
- Effects of home-based exercise on anxiety, depression, cancer-related fatigue, and quality of life in colorectal cancer patients: a meta-analysis of randomized controlled trials.Frontiers in oncology · 2026Review
- Comparative Efficacy of Exercise Interventions for Anxiety Disorders: A Bayesian Network Meta-Analysis.Psychology research and behavior management · 2026Review
- Effects of Home-Based Rehabilitation for Patients With Advanced Lung Cancer Undergoing Platinum-Based Chemotherapy: A Randomized Controlled Trial.Annals of rehabilitation medicine · 2025Article
- Development of a Leg And Walking Self-exercise (LAWS) program for older adults during cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- The effect of different exercise on physical fitness, cognition, and mental health in healthy older adults.Heliyon · 2024Article
- Cardio-oncology rehabilitation: are we ready?European heart journal supplements : journal of the European Society of Cardiology · 2024Article
- Epigenetic and inflammatory markers in older adults with cancer: A Young International Society of Geriatric Oncology narrative review.Journal of geriatric oncology · 2024Review
- Chemotherapy-related symptoms and exercise adherence in older patients with myeloid neoplasms.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Funding
Abstract
BACKGROUND/
objectiveExercise interventions improve anxiety and mood disturbances in patients with cancer. However, studies are limited in older adults with cancer. We assessed the effects of exercise on anxiety, mood, and social and emotional well-being in older patients with cancer during their first 6 weeks of chemotherapy.
designExploratory secondary analysis of a randomized controlled trial (RCT).
settingCommunity oncology practices.
participantsOlder patients (aged 60 years or older) undergoing chemotherapy (N = 252).
interventionPatients were randomized to Exercise for Cancer Patients (EXCAP) or usual care (control) for the first 6 weeks of chemotherapy. EXCAP is a home-based, low- to moderate-intensity progressive walking and resistance training program. MEASUREMENTS: Analysis of covariance, with study arm as the factor, baseline value as the covariate, and study arm × baseline interaction, was used to evaluate arm effects on postintervention anxiety (State Trait Anxiety Inventory [STAI]), mood (Profile of Mood States [POMS]), and social and emotional well-being (Functional Assessment of Cancer Therapy-General subscales) after 6 weeks.
resultsMedian age was 67 years; 77% had breast cancer. Statistically significant group differences were observed in the STAI score (P = .001), POMS score (P = .022), social well-being (P = .002), and emotional well-being (P = .048). For each outcome, EXCAP patients with worse baseline scores had larger improvements at 6 weeks; these improvements were clinically significant for STAI score and social well-being.
conclusionsAmong older cancer patients receiving chemotherapy, a 6-week structured exercise program improved anxiety and mood, especially among those participants with worse baseline symptoms. Additional RCTs are needed to confirm these findings and evaluate the appropriate exercise prescription for managing anxiety, mood, and well-being in this patient population. J Am Geriatr Soc 67:1005-1011, 2019.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.