Evidence map›Paper›PMID 31034160›Full record

ReviewWiley interdisciplinary reviews. RNA2019

RNA regulatory processes in RNA virus biology.

Shaun T Cross, Daniel Michalski, Megan R Miller, Jeffrey Wilusz

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. RNA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Analysis of Leishbuviridae from Trypanosomatids.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Methyltransferases ofBiomolecules · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. NCell discovery · 2021
    Article
  19. Shared properties and singularities of exoribonuclease-resistant RNAs in viruses.Computational and structural biotechnology journal · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shaun T CrossDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado.
Daniel MichalskiDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado.
Megan R MillerDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado.
Jeffrey WiluszDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado.ORCID 0000-0001-8535-3435

Funding

Flavivirus non-coding RNAs and the Host mRNA Decay MachineryR01AI123136 · NIAID · COLORADO STATE UNIVERSITY · PI WILUSZ, JEFFREY · 2016 to 2020
$1.9M
Post-Transcriptional RNA Regulons in Stem CellsR01GM114247 · NIGMS · COLORADO STATE UNIVERSITY · PI WILUSZ, CAROL J, WILUSZ, JEFFREY · 2015 to 2018
$1.2M
Pathological Implications of Repression of Cellular RNA Decay by Zika VirusR21AI130497 · NIAID · COLORADO STATE UNIVERSITY · PI WILUSZ, JEFFREY · 2017 to 2018
$408k
NIAID NIH HHS AI123136NIAID NIH HHS AI39497NIAID NIH HHS R01 AI123136NIAID NIH HHS R21 AI130497NIGMS NIH HHS R01 GM114247
6 · The paper itself

Abstract

Numerous post-transcriptional RNA processes play a major role in regulating the quantity, quality and diversity of gene expression in the cell. These include RNA processing events such as capping, splicing, polyadenylation and modification, but also aspects such as RNA localization, decay, translation, and non-coding RNA-associated regulation. The interface between the transcripts of RNA viruses and the various RNA regulatory processes in the cell, therefore, has high potential to significantly impact virus gene expression, regulation, cytopathology and pathogenesis. Furthermore, understanding RNA biology from the perspective of an RNA virus can shed considerable light on the broad impact of these post-transcriptional processes in cell biology. Thus the goal of this article is to provide an overview of the richness of cellular RNA biology and how RNA viruses use, usurp and/or avoid the associated machinery to impact the outcome of infection. This article is categorized under: RNA in Disease and Development > RNA in Disease.

Indexed as

RNA, ViralRNA VirusesRNA, Viralcappingnon-coding RNAspolyadenylationRNA decayRNA exportRNA methylationRNA virusRNA virus-host interactionssplicingtranslationvirus

Identifiers

PMID31034160
PMCPMC6697219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.