Evidence map›Paper›PMID 31034141›Full record

ArticleHIV medicine2019

Evolution of illicit opioid use among people with HIV infection in St Petersburg, Russia, in the period 2004-2015.

E Blokhina, E M Krupitsky, D M Cheng, A Y Walley, O Toussova, T Yaroslavtseva, N Gnatienko, C Bridden, L S Forman, S Bendiks and 1 more

Open access · greenAbstract read
In one paragraph

Article in HIV medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

E BlokhinaLaboratory of Clinical Pharmacology of Addictions, First Pavlov State Medical University, St Petersburg, Russia.
E M KrupitskyLaboratory of Clinical Pharmacology of Addictions, First Pavlov State Medical University, St Petersburg, Russia.
D M ChengDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
A Y WalleyClinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine/Boston Medical Center, Boston, MA, USA.
O ToussovaLaboratory of Clinical Pharmacology of Addictions, First Pavlov State Medical University, St Petersburg, Russia.
T YaroslavtsevaLaboratory of Clinical Pharmacology of Addictions, First Pavlov State Medical University, St Petersburg, Russia.
N GnatienkoClinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Boston, MA, USA.
C BriddenClinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Boston, MA, USA.
L S FormanBiostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, MA, USA.
S BendiksClinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Boston, MA, USA.ORCID 0000-0002-0769-6106
J H SametClinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine/Boston Medical Center, Boston, MA, USA.
Boston University · USFirst Pavlov State Medical University of St. Petersburg · RUBoston Medical Center · US

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
URBAN ARCH 4/5 Russia Cohort-Targeting HIV-comorbidities with Pharmacotherapy to Reduce Alcohol and Tobacco Use in HIV-infected RussiansU01AA020780 · NIAAA · BOSTON MEDICAL CENTER · PI FREIBERG, MATTHEW S, SAMET, JEFFREY H. · 2011 to 2021
$4.4M
URBAN ARCH (2/5) Biostatistics and Data Management Core (BDM)U24AA020779 · NIAAA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CHENG, DEBBIE M. · 2011 to 2020
$3.6M
URBAN ARCH (1/5) Administrative Coordinating Core (Admin Core)U24AA020778 · NIAAA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2011 to 2020
$3.5M
Linking Russian Narcology & HIV Care to Enhance Treatment, Retention, & OutcomesR01DA032082 · NIDA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2011 to 2015
$3.4M
Maximizing Opportunity - HIV Prevention in Hospitalized Russian DrinkersR01AA016059 · NIAAA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2006 to 2010
$3.2M
HIV Prevention Partnership in Russian Alcohol TreatmentR21AA014821 · NIAAA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H · 2003 to 2005
$1.1M
NIAAA NIH HHS R01 AA016059NIAAA NIH HHS R21 AA014821NIAAA NIH HHS U01 AA020780NIAAA NIH HHS U24 AA020778NIAAA NIH HHS U24 AA020779NIAID NIH HHS P30 AI042853NIDA NIH HHS R01 DA032082
6 · The paper itself

Abstract

objectivesIn the late 1990s, when the current Russian opioid epidemic began, illicit opioids used in Russia consisted almost exclusively of heroin. The type of opioids used has evolved in the early 21st Century. The objective of this study was to describe the evolution of illicit opioid use among people living with HIV (PLWH) reporting recent opioid use in St Petersburg, Russia.

methodsWe examined baseline data from four research studies conducted in the period 2004-2015 that included PLWH who used opioids [Partnership to Reduce the Epidemic Via Engagement in Narcology Treatment (PREVENT; 2004-2005; n = 17), HIV Evolution in Russia-Mitigating Infection Transmission and Alcoholism in a Growing Epidemic (HERMITAGE; 2007-2010; n = 281), Linking Infectious and Narcology Care (LINC; 2013-2014; n = 119) and Russia Alcohol Research Collaboration on HIV/AIDS (Russia ARCH; 2012-2015; n = 121)] and reported recent use of heroin and other opioids.

resultsAlthough these studies spanned more than a decade, the participants represented similar birth cohorts; the mean age was 24.5 years in 2004 and 33.3 years in 2014. The use of opioid types, however, evolved across cohorts, with the use of any illicit drug other than heroin increasing from 6% [95% confidence interval (CI) 000.2, 29%] in PREVENT (2004-2005) to 30% (95% CI 25, 36%) in HERMITAGE (2007-2010) to 70% (95% CI 61, 78%) in LINC (2013-2014) to 77% (95% CI 68, 84%) in ARCH (2012-2015). Any heroin use consistently decreased over the 10-year period in the cohorts, from 100% (95% CI 80, 100%) in 2004-2005 to 54% (95% CI 44, 63%) in 2012-2015.

conclusionsAmong PLWH who use opioids in St Petersburg, Russia, illicit use of opioids other than heroin appears to be more common than heroin use.

Indexed as

HeroinAdultAnalgesics, OpioidCohort StudiesFemaleHIV InfectionsHumansMaleRussiaSubstance Abuse, IntravenousYoung AdultAnalgesics, OpioidHeroinHIVopioid usepeople who inject drugsRussia

Identifiers

PMID31034141
PMCPMC7255405
OpenAlexW2942958722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.