Evidence map›Paper›PMID 31033496›Full record

ArticleApplied immunohistochemistry & molecular morphology : AIMM2020

Recommendations for Tissue Microarray Construction and Quality Assurance.

Betty Glinsmann-Gibson, Lee Wisner, Melissa Stanton, Brandon Larsen, Lisa Rimsza, Alanna Maguire

Abstract read
In one paragraph

Article in Applied immunohistochemistry & molecular morphology : AIMM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Betty Glinsmann-GibsonDepartments of Research.
Lee WisnerDepartments of Research.
Melissa StantonLaboratory Medicine and Pathology, Mayo Clinic Arizona, Scottsdale, AZ.
Brandon LarsenLaboratory Medicine and Pathology, Mayo Clinic Arizona, Scottsdale, AZ.
Lisa RimszaLaboratory Medicine and Pathology, Mayo Clinic Arizona, Scottsdale, AZ.
Alanna MaguireDepartments of Research.

Funding

AIDS and Cancer Specimen Resource (ACSR)UM1CA181255 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jeffrey Michael Bethony, Anna Coghill · 2013 to 2026
$56.7M
NCI NIH HHS UM1 CA181255
6 · The paper itself

Abstract

Tissue microarrays (TMAs) are important tools to conserve precious tissue resources from increasingly smaller biopsies and to control experimental costs and variation across sample sets. The quality assurance assessment of TMA materials created at centralized biobanks has not been standardized. Herein, we outline 2 processes for the construction of TMAs ("recipient block" and "tape" methods) and the associated preconstruction quality control measures (pathology review, protein and RNA assessment, map creation, and storage conditions) developed by the AIDS Cancer Specimen Resource (ACSR) Network's Science and Technology Core. These steps provide a suggested framework for quality assessment that allows end-users, receiving materials from tissue banks, confidence in their experimental results.

Indexed as

Paraffin EmbeddingQuality ControlTissue Array AnalysisHumans

Identifiers

PMID31033496
PMCPMC6813869

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.