Evidence map›Paper›PMID 31033442›Full record

ArticleeLife2019

Single cell, super-resolution imaging reveals an acid pH-dependent conformational switch in SsrB regulates SPI-2.

Andrew Tze Fui Liew, Yong Hwee Foo, Yunfeng Gao, Parisa Zangoui, Moirangthem Kiran Singh, Ranjit Gulvady, Linda J Kenney

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Regulator-derived growth and fitness costs ofbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Experimental Approaches to Visualize Effector Protein Translocation During Host-Pathogen Interactions.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Computerized fluorescence microscopy of microbial cells.World journal of microbiology & biotechnology · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrew Tze Fui Liew *Mechanobiology Institute, T-Lab, National University of Singapore, Singapore, Singapore.ORCID 0000-0003-4792-9637
Yong Hwee Foo *Mechanobiology Institute, T-Lab, National University of Singapore, Singapore, Singapore.ORCID 0000-0003-2337-469X
Yunfeng GaoMechanobiology Institute, T-Lab, National University of Singapore, Singapore, Singapore.
Parisa ZangouiMechanobiology Institute, T-Lab, National University of Singapore, Singapore, Singapore.
Moirangthem Kiran SinghMechanobiology Institute, T-Lab, National University of Singapore, Singapore, Singapore.ORCID 0000-0001-9620-5454
Ranjit GulvadyMechanobiology Institute, T-Lab, National University of Singapore, Singapore, Singapore.
Linda J KenneyMechanobiology Institute, T-Lab, National University of Singapore, Singapore, Singapore.ORCID 0000-0002-8658-0717

Funding

Dual Roles for the Salmonella SPI-2 Regulator SsrBR21AI123640 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KENNEY, LINDA J. · 2016 to 2017
$422k
NIAID NIH HHS R21 AI123640NIH HHS AI-123640
6 · The paper itself

Abstract

After

Indexed as

Hydrogen-Ion ConcentrationAcidsBacterial ProteinsCytoplasmDNA-Binding ProteinsGene Expression Regulation, BacterialHistidine KinaseMembrane ProteinsMolecular ConformationPromoter Regions, GeneticSalmonella typhimuriumTrans-ActivatorsTranscription FactorsVacuolesVirulenceAcidsBacterial ProteinsDNA-Binding ProteinsHistidine KinaseMembrane ProteinsompR protein, Salmonella typhimuriumPhoP protein, BacteriaSPI-2 protein, SalmonellassrA protein, Salmonella typhimuriumSsrB protein, Salmonella typhimuriumTrans-ActivatorsTranscription Factorsinfectious disease<i>s. enterica</i> serovar typhimicrobiologySalmonellasingle molecule unzippingsingle particle trackingSPI-2SsrBsuper-resolution microscopy

Identifiers

PMID31033442
PMCPMC6557628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.