Evidence map›Paper›PMID 31033242›Full record

ArticleBrain and behavior2019

Restraint devices for repetitive transcranial magnetic stimulation in mice and rats.

Chengliang Zhang, Rulan Lu, Linxiao Wang, Wenwei Yun, Xianju Zhou

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Tumor suppressive effect of low-frequency repetitive transcranial magnetic stimulation on glioblastoma progression.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
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  6. [Effects of magnetic stimulation at different frequencies on neuronal excitability and voltage-gated potassium channelsSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chengliang ZhangLaboratory of Neurological, Department of Neurology, The affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou, China.
Rulan LuLaboratory of Neurological, Department of Neurology, The affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou, China.
Linxiao WangLaboratory of Neurological, Department of Neurology, The affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou, China.
Wenwei YunLaboratory of Neurological, Department of Neurology, The affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou, China.
Xianju ZhouLaboratory of Neurological, Department of Neurology, The affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou, China.ORCID 0000-0003-1744-556X
Changzhou No.2 People's Hospital · CNTCM-Intigrated Cancer Center of Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRepetitive transcranial magnetic stimulation has been widely used for the treatment of neurological and psychiatric diseases. Rodent animals including mice and rats are often used to investigate the potential cellular and molecular mechanisms for the therapeutic effects of repetitive transcranial magnetic stimulation. So far there is no report about an easy-to-use device to restrain rodent animals for repetitive transcranial magnetic stimulation. METHODS AND

resultsWe introduced the design and use of the restraint device for mice or rats. In the mouse device, western blot and real-time PCR analysis showed that,in stimulated mouse frontal cortex, 10 Hz high frequency stimulation for 10 sessions resulted in enhanced expression of NR2B-containing N-methyl-D-aspartic acid receptors and reduced α1 subunit of inhibitory GABA

conclusionsThese results suggested the effectiveness of the devices. Thus, the two devices are practical and easy-to-use to investigate the mechanisms of repetitive transcranial magnetic stimulation.

Indexed as

AnimalsEquipment DesignEvoked Potentials, MotorMaleMice, Inbred C57BLMotor CortexRats, Sprague-DawleyReceptors, N-Methyl-D-AspartateRestraint, PhysicalTranscranial Magnetic StimulationNR2B NMDA receptorReceptors, N-Methyl-D-Aspartatemouseratrepetitive transcranial magnetic stimulationrestraint device

Identifiers

PMID31033242
PMCPMC6576213
OpenAlexW2943677616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.