ArticleCNS neuroscience & therapeutics2019
Deep brain stimulation in post-traumatic dystonia: A case series study.
Article in CNS neuroscience & therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Successful treatment of focal hand dystonia after cervical whiplash injury by thalamotomy.Surgical neurology international · 2022Article
- Deep brain stimulation in post-traumatic dystonia: A case series study.CNS neuroscience & therapeutics · 2019Article
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Authors and funding
9 authors.
Funding
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Abstract
aimsDeep brain stimulation (DBS) has been proposed as an effective treatment for drug-intolerant isolated dystonia, but whether it is also efficacious for posttraumatic dystonia (PTD) is unknown. Reports are few in number and have reached controversial conclusions regarding the efficacy of DBS for PTD treatment. Here, we report a case series of five PTD patients with improved clinical benefit following DBS treatment.
methodsFive patients with disabling PTD underwent DBS therapy. The clinical outcomes were assessed with the Burke-Fahn-Marsden dystonia rating scale (BFMDRS) at baseline and the last follow-up visit (at more than 12 months).
resultsPatients 1 and 3 received unilateral globus pallidus internus (GPi) DBS for contralateral dystonia. The subthalamic nucleus (STN) was chosen as target for patients 2 and 4, due to a lesion located in the globus pallidus. Patient 5 had an electrode in the ventral intermediate nucleus (VIM) for treating predominant tremor of left upper extremity, with unexpected improvement of focal hand dystonia. The scores of BFMDRS movement exhibited favorable improvement in all five patients at the last follow-up, ranging from 52.4% to 78.6%.
conclusionsDeep brain stimulation may be an effective and safe treatment for medically refractory PTD, but this needs to be confirmed by further studies.
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