Evidence map›Paper›PMID 31033159›Full record

ArticleJournal of applied clinical medical physics2019

A Helical tomotherapy as a robust low-dose treatment alternative for total skin irradiation.

André Haraldsson, Jens Engleson, Sven Å J Bäck, Silke Engelholm, Per E Engström

Abstract readCase Reports
In one paragraph

Article in Journal of applied clinical medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Total skin electron beam therapy.Frontiers in oncology · 2025
    Article
  5. Application of deblur technology for improving the clarity of digital subtractive angiography.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Article
  6. Article
  7. Total Skin Treatment with Helical Arc Radiotherapy.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

André HaraldssonDepartment of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.
Jens EnglesonDepartment of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.
Sven Å J BäckDepartment of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.
Silke EngelholmDepartment of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.
Per E EngströmDepartment of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.

Funding

Accuray Inc.
6 · The paper itself

Abstract

Mycosis fungoides is a disease with manifestation of the skin that has traditionally been treated with electron therapy. In this paper, we present a method of treating the entire skin with megavoltage photons using helical tomotherapy (HT), verified through a phantom study and clinical dosimetric data from our first two treated patients. A whole body phantom was fitted with a wetsuit as bolus, and scanned with computer tomography. We accounted for variations in daily setup using virtual bolus in the treatment plan optimization. Positioning robustness was tested by moving the phantom, and recalculating the dose at different positions. Patient treatments were verified with in vivo film dosimetry and dose reconstruction from daily imaging. Reconstruction of the actual delivered dose to the patients showed similar target dose as the robustness test of the phantom shifted 10 mm in all directions, indicating an appropriate approximation of the anticipated setup variation. In vivo film measurements agreed well with the calculated dose confirming the choice of both virtual and physical bolus parameters. Despite the complexity of the treatment, HT was shown to be a robust and feasible technique for total skin irradiation. We believe that this technique can provide a viable option for Tomotherapy centers without electron beam capability.

Indexed as

Phantoms, ImagingAdultAgedFeasibility StudiesFemaleHumansImage Processing, Computer-AssistedMaleMycosis FungoidesPrognosisRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedSkin NeoplasmsTomography, X-Ray Computedfungoideshelicalmycosisskintomotherapytotal skin irradiation

Identifiers

PMID31033159
PMCPMC6522990

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.