Evidence map›Paper›PMID 31033084›Full record

ArticleAddiction (Abingdon, England)2019

Changes in associations of prescription opioid use disorder and illegal behaviors among adults in the United States from 2002 to 20.

Carrie M Mintz, Sarah M Hartz, Jacob T Borodovsky, Laura J Bierut, Richard A Grucza

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Carrie M MintzDepartment of Psychiatry, Washington University in St Louis School of Medicine, St Louis, MO, USA.ORCID 0000-0001-5291-9690
Sarah M HartzDepartment of Psychiatry, Washington University in St Louis School of Medicine, St Louis, MO, USA.
Jacob T BorodovskyDepartment of Psychiatry, Washington University in St Louis School of Medicine, St Louis, MO, USA.ORCID 0000-0001-7112-5677
Laura J BierutDepartment of Psychiatry, Washington University in St Louis School of Medicine, St Louis, MO, USA.
Richard A GruczaDepartment of Psychiatry, Washington University in St Louis School of Medicine, St Louis, MO, USA.ORCID 0000-0002-8191-6875
Washington University in St. Louis · US

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI JESSICA E SALVATORE · 1989 to 2026
$162.7M
National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
BIOMEDICAL RESEARCH TRAINING IN DRUG ABUSET32DA007261 · NIDA · WASHINGTON UNIVERSITY · PI ARPANA AGRAWAL, Jose A Moron-Concepcion · 1991 to 2026
$8.8M
Washington University Career Development Program in Drug Abuse and AddictionK12DA041449 · NIDA · WASHINGTON UNIVERSITY · PI Laura J. Bierut, Patricia A Cavazos-Rehg · 2017 to 2026
$4.2M
Nicotine Dependence to Smoking Cessation: Sequencing Common and Rare VariantsR01DA036583 · NIDA · WASHINGTON UNIVERSITY · PI BIERUT, LAURA J. · 2014 to 2017
$3.0M
AN EXAMINATION OF AGE-RELATED DISPARITIES IN MEDICATION ASSISTED TREATMENT AND ASSOCIATED OUTCOMESR21DA044744 · NIDA · WASHINGTON UNIVERSITY · PI BIERUT, LAURA J. · 2017 to 2018
$419k
THE SHARED GENETICS OF ALCOHOL-RELATED DISORDERS AND SCHIZOPHRENIAR21AA024888 · NIAAA · WASHINGTON UNIVERSITY · PI HARTZ, SARAH · 2017 to 2018
$417k
USING TEMPORAL VARIATION IN RISK BEHAVIOR TO UNDERSTAND TRENDS IN ADOLESCENT ALCOHOL MISUSER21AA025689 · NIAAA · WASHINGTON UNIVERSITY · PI GRUCZA, RICHARD A · 2018 to 2019
$416k
NCATS NIH HHS UL1 TR002345NIAAA NIH HHS R21 AA024888NIAAA NIH HHS R21 AA025689NIAAA NIH HHS U10 AA008401NIA NIH HHS U24 AG021886NIDA NIH HHS K12 DA041449NIDA NIH HHS R01 DA036583NIDA NIH HHS R21 DA044744NIDA NIH HHS T32 DA007261NIH HHS R21AA02568901
6 · The paper itself

Abstract

BACKGROUND AND

aimsIn the United States, the availability of prescription opioids has decreased in recent years. Whether there have been corresponding changes in the likelihood of people with prescription opioid use disorder (POUD) to engage in illegal behaviors related to drug use remains unknown. We examined changes in prevalence of illegal behaviors between people with and without POUD over time, and how transactions for obtaining opioids have changed among people with POUD over time.

designTemporal trend analysis of repeated cross-sectional data.

settingUnited States household dwelling population from all 50 states and District of Columbia.

participantsAdult subsamples from the 2002-14 National Survey of Drug Use and Health (n = 5393 people with POUD; n = 486 768 people without POUD). MEASUREMENTS: Outcome variables were selected illegal behaviors and sources of opioids used non-medically. POUD was defined using the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, criteria. Time was treated as a continuous variable. The variable of interest for each illegal behavior analysis was the interaction between POUD diagnosis and time. Covariates included age, sex and race/ethnicity.

findingsDuring the 13-year period examined, the adjusted interaction odds ratio (AIOR) describing the change in association between POUD and selling illicit drugs increased by a factor of 2.41 [95% confidence interval (CI) = 1.56-3.71, P < 0.001]. Similar trends were noted for stealing (AIOR = 2.12, 95% CI = 1.31-3.44, P = 0.002) and for life-time history of arrest (AIOR = 1.53, 95% CI = 1.06-2.19, P = 0.021). People with POUD became less likely to receive opioids for free from friends and family [adjusted odds ratio (AOR) = 0.42, 95% CI = 0.25-0.71, P = 0.001] and more likely to buy them from friends and family (AOR = 3.29, 95% CI = 1.76-6.13, P < 0.001) from 2005 to 2014.

conclusionsIn the United States, against a backdrop of a decreasing prescription opioid supply, rates of some crimes potentially related to drug use increased among people with prescription opioid use disorder compared with those without prescription opioid use disorder from 2002 to 2014.

Indexed as

Criminal BehaviorAdolescentAdultAnalgesics, OpioidCrimeCross-Sectional StudiesFemaleHealth SurveysHumansMaleMiddle AgedOdds RatioOpioid-Related DisordersPrescription Drug MisusePrevalenceUnited StatesAnalgesics, OpioidCrimedrug policyillegal behaviornon-medical opioid sourceopioid use disorderprescription opioid use disorder

Identifiers

PMID31033084
PMCPMC6819203
OpenAlexW2942713474

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.