Evidence map›Paper›PMID 31032849›Full record

ArticleBrain : a journal of neurology2019

Novel GABRA2 variants in epileptic encephalopathy and intellectual disability with seizures.

Snezana Maljevic, Boris Keren, Ye Htet Aung, Ian C Forster, Cyril Mignot, Julien Buratti, Aurélie Lafitte, Cécile Freihuber, Lance H Rodan, Ann Bergin and 13 more

Open access · bronzeAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in Brain : a journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 7 institutions in 4 countries.

Snezana MaljevicThe Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia.
Boris KerenAPHP, Hôpital Pitié-Salpêtrière, Département de Génétique, Centre de Reference Déficience Intellectuelle de Causes Rares, GRC UPMC «Déficience Intellectuelle et Autisme», Paris, France.
Ye Htet AungThe Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia.
Ian C ForsterThe Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia.
Cyril MignotAPHP, Hôpital Pitié-Salpêtrière, Département de Génétique, Centre de Reference Déficience Intellectuelle de Causes Rares, GRC UPMC «Déficience Intellectuelle et Autisme», Paris, France.
Julien BurattiAPHP, Hôpital Pitié-Salpêtrière, Département de Génétique, Centre de Reference Déficience Intellectuelle de Causes Rares, GRC UPMC «Déficience Intellectuelle et Autisme», Paris, France.
Aurélie LafitteAPHP, Hôpital Pitié-Salpêtrière, Département de Génétique, Centre de Reference Déficience Intellectuelle de Causes Rares, GRC UPMC «Déficience Intellectuelle et Autisme», Paris, France.
Cécile FreihuberAP-HP, Hôpital Trousseau, Service de Neuropédiatrie, Paris, France.
Lance H RodanDivision of Genetics and Genomics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Ann BerginDivision of Epilepsy and Clinical Neurophysiology, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Laurence HubertINSERM UMR 1163, Translational Genetics Lab., Paris-Descartes University, Imagine Institute, Paris, France.
Karine PoirierINSERM UMR 1163, Translational Genetics Lab., Paris-Descartes University, Imagine Institute, Paris, France.
Arnold MunnichINSERM UMR 1163, Translational Genetics Lab., Paris-Descartes University, Imagine Institute, Paris, France.
Claude BesmondINSERM UMR 1163, Translational Genetics Lab., Paris-Descartes University, Imagine Institute, Paris, France.
Natalie HauserInova Health System, Inova Translational Medicine Institute, Falls Church, VA, USA.
Rebecca MillerInova Health System, Inova Translational Medicine Institute, Falls Church, VA, USA.
Kirsty McWalterGeneDx, Gaithersburg, Maryland, USA.
Rima NabboutAPHP, Hôpital Necker Enfants Malades, Centre de référence épilepsies rares, Service de Neurologie pédiatrique, Paris, France.
Delphine HéronAPHP, Hôpital Pitié-Salpêtrière, Département de Génétique, Centre de Reference Déficience Intellectuelle de Causes Rares, GRC UPMC «Déficience Intellectuelle et Autisme», Paris, France.
Eric LeguernAPHP, Hôpital Pitié-Salpêtrière, Département de Génétique, Centre de Reference Déficience Intellectuelle de Causes Rares, GRC UPMC «Déficience Intellectuelle et Autisme», Paris, France.
Christel DepienneSorbonne Universités, Institut du Cerveau et de la Moelle épinière, ICM, Inserm U1127, CNRS UMR 7225, F-75013, Paris, France.
Steven PetrouThe Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia.
Caroline NavaAPHP, Hôpital Pitié-Salpêtrière, Département de Génétique, Centre de Reference Déficience Intellectuelle de Causes Rares, GRC UPMC «Déficience Intellectuelle et Autisme», Paris, France.
Sorbonne Université · FRCentre National de la Recherche Scientifique · FRInserm · FRThe University of Melbourne · AUBoston Children's Hospital · USInova Health System · USHôpital Necker-Enfants Malades · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EpilepsyEpilepsy, GeneralizedIntellectual DisabilityHumansReceptors, GABA-ASeizuresGABRA2 protein, humanReceptors, GABA-A

Identifiers

PMID31032849
OpenAlexW2936355378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.