Evidence map›Paper›PMID 31032821›Full record

ArticleRevista espanola de salud publica2019

[Effectiveness of annual flu vaccination until week four of season 2018/2019].

Paula Gras-Valentí, Natividad Algado-Sellés, Pablo Chico-Sánchez, Ginger Giorgiana Cabrera-Tejada, Juan Carlos Rodríguez-Díaz, José Sánchez-Payá

Abstract read
In one paragraph

Article in Revista espanola de salud publica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paula Gras-ValentíUnidad de Epidemiología. Servicio de Medicina Preventiva. Hospital General Universitario de Alicante. Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL ). Alicante. España.
Natividad Algado-SellésUnidad de Epidemiología. Servicio de Medicina Preventiva. Hospital General Universitario de Alicante. Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL ). Alicante. España.
Pablo Chico-SánchezUnidad de Epidemiología. Servicio de Medicina Preventiva. Hospital General Universitario de Alicante. Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL ). Alicante. España.
Ginger Giorgiana Cabrera-TejadaUnidad de Epidemiología. Servicio de Medicina Preventiva. Hospital General Universitario de Alicante. Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL ). Alicante. España.
Juan Carlos Rodríguez-DíazServicio de Microbiología. Hospital General Universitario de Alicante. Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL ). Alicante. España.
José Sánchez-PayáUnidad de Epidemiología. Servicio de Medicina Preventiva. Hospital General Universitario de Alicante. Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL ). Alicante. España.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAnnual flu vaccination is the most effective measure to prevent the disease and its complications. Vaccine effectiveness (EV) varies from season to season, requiring annual re-evaluation. The objective of this work was to estimate the preliminary effectiveness of the influenza vaccine until epidemiological week 4 of the 2018/2019 season, in patients admitted to a third level hospital.

methodsThe Test Negative Design (TDN) was carried out at the Hospital General Universitario de Alicante. Patients admitted with laboratory-confirmed influenza (RT-PCR positive for any influenza virus, in clinical sample of nasopharyngeal aspirate) and those with clinical suspicion of influenza and negative RT-PCR, from week 40 to week 4 of the 2018/2019 influenza season, were considered as controls. The vaccination coverage was calculated in the cases and in the controls, and the EV with its 95% confidence interval using the formula: EV = (1-Odds Ratio) x 100.

resultsWe included 524 patients: 58 cases and 466 controls. The overall EV for prevention of influenza cases was 42.5 % (95% CI -17.1 to 71.8) and for those over 1 year of age 63.7 % (95% CI 25.4 to 82.3).

conclusionsThe 2018-2019 influenza vaccine is effective in preventing influenza cases in patients admitted up to week 4 of the 2018-19 season. Results are preliminary and may vary and should be re-evaluated at the end of the season.

Indexed as

Influenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza VaccinesSeasonsAdolescentAdultAgedAged, 80 and overCase-Control StudiesChildChild, PreschoolFemaleHospitalizationHumansInfantInfluenza, HumanInfluenza VaccinesHumanInfluenzaInfluenza vaccinesSpainTreatment outcomeVaccinationVaccination coverage

Identifiers

PMID31032821
PMCPMC11582833

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.