Evidence map›Paper›PMID 31032819›Full record

ReviewInternational journal of molecular sciences2019

Experimental Models of Brugada syndrome.

Franziska Sendfeld, Elisabet Selga, Fabiana S Scornik, Guillermo J Pérez, Nicholas L Mills, Ramon Brugada

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Zebrafish as a Model System for Brugada Syndrome.Reviews in cardiovascular medicine · 2024
    Review
  3. Multisite Validation of a Functional Assay to AdjudicateCirculation. Genomic and precision medicine · 2024
    Article
  4. Article
  5. Brugada syndrome update.Frontiers in physiology · 2024
    Review
  6. Multi-site validation of a functional assay to adjudicatemedRxiv : the preprint server for health sciences · 2023
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Alterations of the Sialylation Machinery in Brugada Syndrome.International journal of molecular sciences · 2022
    Article
  12. Article
  13. Review
  14. ESC working group on cardiac cellular electrophysiology position paper: relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2021
    Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Franziska SendfeldScottish Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, EH16 4UU, UK. f.sendfeld@gmail.com.
Elisabet SelgaFaculty of Medicine, University of Vic-Central University of Catalonia (UVic-UCC), Vic, 08500, Spain. eselga@gencardio.com.
Fabiana S ScornikDepartment of Medical Sciences, Faculty of Medicine, Universitat de Girona (UdG), Girona 17071, Spain. fabianasilvia.scornik@udg.edu.
Guillermo J PérezDepartment of Medical Sciences, Faculty of Medicine, Universitat de Girona (UdG), Girona 17071, Spain. guillermo.perez@udg.edu.
Nicholas L MillsBHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, EH16 4TJ, UK. nick.mills@ed.ac.uk.
Ramon BrugadaDepartment of Medical Sciences, Faculty of Medicine, Universitat de Girona (UdG), Girona 17071, Spain. rbrugada@idibgi.org.
Universitat de Girona · ESMRC Centre for Regenerative Medicine · GBUniversitat de Vic - Universitat Central de Catalunya · ESUniversity of Edinburgh · GB

Funding

British Heart Foundation FS/10/024/28266British Heart Foundation FS/16/14/32023Cardiovascular Regenerative Medicine Centre RM/13/2/30158Centro Nacional de Investigaciones Cardiovasculares CNIC-03-2008CIBERCV n/aFundació La Marató de TV3 20153910Instituto de Salud Carlos III FIS-PI08/1800"la Caixa" Foundation n/aUniversitat de Girona MPCUdG2016
6 · The paper itself

Abstract

Brugada syndrome is an inherited, rare cardiac arrhythmogenic disease, associated with sudden cardiac death. It accounts for up to 20% of sudden deaths in patients without structural cardiac abnormalities. The majority of mutations involve the cardiac sodium channel gene

Indexed as

Disease Models, AnimalAnimalsAnimals, Genetically ModifiedBiomarkersBrugada SyndromeCell DifferentiationDisease SusceptibilityDogsGenetic Predisposition to DiseaseHumansInduced Pluripotent Stem CellsMiceMutationMyocytes, CardiacNAV1.5 Voltage-Gated Sodium ChannelBiomarkersNAV1.5 Voltage-Gated Sodium ChannelBrugada syndromeinduced pluripotent stem cells (iPS)model systemsSCN5A

Identifiers

PMID31032819
PMCPMC6539778
OpenAlexW2942810200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.