Evidence map›Paper›PMID 31032640›Full record

ArticleNatural product research2021

Activity of natural and synthetic polygodial derivatives against

Danielle N Turner, Jeremy Just, Ramesh Dasari, Jason A Smith, Alex C Bissember, Alexander Kornienko, Snezna Rogelj

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Natural product research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Plant Terpenoids as Hit Compounds against Trypanosomiasis.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  4. Parasitology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Danielle N TurnerDepartment of Biology, New Mexico Tech, Socorro, New Mexico, USA.
Jeremy JustSchool of Natural Sciences - Chemistry, University of Tasmania, Hobart, Tasmania, Australia.
Ramesh DasariDepartment of Chemistry and Biochemistry, Texas State University, San Marcos, Texas, USA.
Jason A SmithSchool of Natural Sciences - Chemistry, University of Tasmania, Hobart, Tasmania, Australia.
Alex C BissemberSchool of Natural Sciences - Chemistry, University of Tasmania, Hobart, Tasmania, Australia.
Alexander KornienkoDepartment of Chemistry and Biochemistry, Texas State University, San Marcos, Texas, USA.
Snezna RogeljDepartment of Biology, New Mexico Tech, Socorro, New Mexico, USA.
University of Tasmania · AUNew Mexico Institute of Mining and Technology · USTexas State University · US

Funding

NM-INBRE Sequencing and Bioinformatics CoreP20GM103451 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI Charlotte C. Gard · 2012 to 2026
$61.2M
NIGMS NIH HHS P20 GM103451
6 · The paper itself

Abstract

Our laboratories have been investigating biological effects of a sesquiterpenoid polygodial and its natural and synthetic analogues. Herein, we report the evaluation of these compounds against the three forms of

Indexed as

AnimalsCell LineHumansLife Cycle StagesNitroimidazolesSesquiterpenesTrypanocidal AgentsTrypanosoma cruzibenzonidazoleNitroimidazolespolygodialSesquiterpenesTrypanocidal Agentsanti-parasiticphosphonatepolygodialterpenesTrypanosoma cruziWittig derivatives

Identifiers

PMID31032640
PMCPMC7182085
OpenAlexW2942770339

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.