Evidence map›Paper›PMID 31032487›Full record

ArticleComputational Science--ICCS ... : international conference ... : proceedings. ICCS2018

A Computational Model-Based Framework to Plan Clinical Experiments - an Application to Vascular Adaptation Biology.

Stefano Casarin, Scott A Berceli, Marc Garbey

Abstract read
In one paragraph

Article in Computational Science--ICCS ... : international conference ... : proceedings. ICCS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Stefano CasarinLASIE UMR 7356 CNRS, University of La Rochelle, La Rochelle, France.
Scott A BerceliDepartment of Surgery, University of Florida, Gainesville, FL, USA.
Marc GarbeyLASIE UMR 7356 CNRS, University of La Rochelle, La Rochelle, France.
Houston Methodist · USMalcom Randall VA Medical Center · USMethodist Hospital · US

Funding

Constitutive and Agent-Based Multiscale Models to Improve Vein Graft SurvivalU01HL119178 · NHLBI · UNIVERSITY OF FLORIDA · PI BERCELI, SCOTT A, GARBEY, MARC · 2013 to 2018
$2.7M
NHLBI NIH HHS U01 HL119178
6 · The paper itself

Abstract

Several computational models have been developed in order to improve the outcome of Vein Graft Bypasses in response to arterial occlusions and they all share a common property: their accuracy relies on a winning choice of the coefficients' value related to biological functions that drive them. Our goal is to optimize the retrieval of these unknown coefficients on the base of experimental data and accordingly, as biological experiments are noisy in terms of statistical analysis and the models are typically stochastic and complex, this work wants first to elucidate which experimental measurements might be sufficient to retrieve the targeted coefficients and second how many specimens would constitute a good dataset to guarantee a sufficient level of accuracy. Since experiments are often costly and time consuming, the planning stage is critical to the success of the operation and, on the base of this consideration, the present work shows how, thanks to an

Indexed as

Agent Based ModelExperiment PlanningVirtual Dataset

Identifiers

PMID31032487
PMCPMC6482970
OpenAlexW2808143692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.