Evidence map›Paper›PMID 31032483›Full record

ArticleGlobal transitions2019

A roadmap for semi-automatically extracting predictive and clinically meaningful temporal features from medical data for predictive modeling.

Gang Luo

Abstract read
In one paragraph

Article in Global transitions, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gang LuoDepartment of Biomedical Informatics and Medical Education, University of Washington, UW Medicine South Lake Union, 850 Republican Street, Building C, Box 358047, Seattle, WA, 98109, USA luogang@uw.edu.

Funding

Using Computational Approaches to Optimize Asthma Care ManagementR01HL142503 · NHLBI · UNIVERSITY OF WASHINGTON · PI LUO, GANG · 2018 to 2021
$3.3M
NHLBI NIH HHS R01 HL142503
6 · The paper itself

Abstract

Predictive modeling based on machine learning with medical data has great potential to improve healthcare and reduce costs. However, two hurdles, among others, impede its widespread adoption in hdealthcare. First, medical data are by nature longitudinal. Pre-processing them, particularly for feature engineering, is labor intensive and often takes 50-80% of the model building effort. Predictive temporal features are the basis of building accurate models, but are difficult to identify. This is problematic. Healthcare systems have limited resources for model building, while inaccurate models produce sub-optimal outcomes and are often useless. Second, most machine learning models provide no explanation of their prediction results. However, offering such explanations is essential for a model to be used in usual clinical practice. To address these two hurdles, this paper outlines: 1) a data-driven method for semi-automatically extracting predictive and clinically meaningful temporal features from medical data for predictive modeling; and 2) a method of using these features to automatically explain machine learning prediction results and suggest tailored interventions. This provides a roadmap for future research.

Indexed as

Automatic explanationMachine learningMedical dataPredictive modelingRecurrent neural networkTemporal feature

Identifiers

PMID31032483
PMCPMC6482973

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.