Evidence map›Paper›PMID 31032427›Full record

ArticleElectrospinning2018

Solvent retention in electrospun fibers affects scaffold mechanical properties.

Anthony R D'Amato, Michael T K Bramson, Devan L Puhl, Jed Johnson, David T Corr, Ryan J Gilbert

Open access · bronzeAbstract read
In one paragraph

Article in Electrospinning, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Application of PLCL as a biodegradable polymer in biomedical engineering.Journal of materials science. Materials in medicine · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anthony R D'AmatoDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 8th St., Troy, New York 12180, United States of America; Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, 1623 15th Street, Troy, New York 12180, United States of America.
Michael T K BramsonDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 8th St., Troy, New York 12180, United States pf America.
Devan L PuhlDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 8th St., Troy, New York 12180, United States of America; Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, 1623 15th Street, Troy, New York 12180, United States of America.
Jed JohnsonNanofiber Solutions, 4389 Weaver Court North, Hilliard, OH 43026, United States of America.
David T CorrDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 8th St., Troy, New York 12180, United States pf America.
Ryan J GilbertDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 8th St., Troy, New York 12180, United States of America; Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, 1623 15th Street, Troy, New York 12180, United States of America.
Rensselaer Polytechnic Institute · USNanofiber Solutions (United States) · US

Funding

Enhanced Neuroprotection Following Acute SCI Using Fibrous MaterialsR01NS092754 · NINDS · RENSSELAER POLYTECHNIC INSTITUTE · PI GILBERT, RYAN J. · 2015 to 2019
$1.3M
NINDS NIH HHS R01 NS092754
6 · The paper itself

Abstract

Electrospinning is a robust material fabrication method allowing for fine control of mechanical, chemical, and functional properties in scaffold manufacturing. Electrospun fiber scaffolds have gained prominence for their potential in a variety of applications such as tissue engineering and textile manufacturing, yet none have assessed the impact of solvent retention in fibers on the scaffold's mechanical properties. In this study, we hypothesized that retained electrospinning solvent acts as a plasticizer, and gradual solvent evaporation, by storing fibers in ambient air, will cause significant increases in electrospun fiber scaffold brittleness and stiffness, and a significant decrease in scaffold toughness. Thermogravimetric analysis indicated solvent retention in PGA, PLCL, and PET fibers, and not in PU and PCL fibers. Differential scanning calorimetry revealed that polymers that were electrospun below their glass transition temperature (T

Indexed as

Electrospun fibersmechanical characterizationSolvent retention

Identifiers

PMID31032427
PMCPMC6482971
OpenAlexW2897854326

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.