ArticleScience advances2019
Synthetic and living micropropellers for convection-enhanced nanoparticle transport.
Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed.
- Magnetic DNA Origami Nanorotors.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Machine-intelligent multimodal algebot for intracavitary chemotherapy.Nature nanotechnology · 2026Article
- Article
- Microbiome-targeted nanoplatforms and engineering approaches in breast cancer therapy.Molecular cancer · 2025Review
- Magnetically Driven Living Microrobot Swarms for Aquatic Micro- and Nanoplastic Cleanup.ACS nano · 2025Article
- Engineering Magnetotactic Bacteria as Medical Microrobots.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Magnetite Micro/Nanorobots for Efficient Targeted Alleviation of Inflammatory Bowel Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Microgripper Robot with End Electropermanent Magnet Collaborative Actuation.Micromachines · 2024Article
- Spatially selective delivery of living magnetic microrobots through torque-focusing.Nature communications · 2024Article
- State of the Art in Actuation of Micro/Nanorobots for Biomedical Applications.Small science · 2024Article
- Inductive sensing of magnetic microrobots under actuation by rotating magnetic fields.PNAS nexus · 2023Article
- Advances of medical nanorobots for future cancer treatments.Journal of hematology & oncology · 2023Review
- Engineered bacterial swarm patterns as spatial records of environmental inputs.Nature chemical biology · 2023Article
- Self-propelling colloids with finite state dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Ultrafast Miniature Robotic Swimmers with Upstream Motility.Cyborg and bionic systems (Washington, D.C.) · 2023Article
- Assessing the interactions between nanoparticles and biological barriers in vitro: a new challenge for microscopy techniques in nanomedicine.European journal of histochemistry : EJH · 2022Article
- In Vitro Models of Biological Barriers for Nanomedical Research.International journal of molecular sciences · 2022Review
- In vitro magnetosome remineralization for silver-magnetite hybrid magnetosome biosynthesis and used for healing of the infected wound.Journal of nanobiotechnology · 2022Article
- Mobile Nanobots for Prevention of Root Canal Treatment Failure.Advanced healthcare materials · 2022Article
- Review
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Nanoparticles (NPs) have emerged as an advantageous drug delivery platform for the treatment of various ailments including cancer and cardiovascular and inflammatory diseases. However, their efficacy in shuttling materials to diseased tissue is hampered by a number of physiological barriers. One hurdle is transport out of the blood vessels, compounded by difficulties in subsequent penetration into the target tissue. Here, we report the use of two distinct micropropellers powered by rotating magnetic fields to increase diffusion-limited NP transport by enhancing local fluid convection. In the first approach, we used a single synthetic magnetic microrobot called an artificial bacterial flagellum (ABF), and in the second approach, we used swarms of magnetotactic bacteria (MTB) to create a directable "living ferrofluid" by exploiting ferrohydrodynamics. Both approaches enhance NP transport in a microfluidic model of blood extravasation and tissue penetration that consists of microchannels bordered by a collagen matrix.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.