ArticleScience advances2019
Rehearsal initiates systems memory consolidation, sleep makes it last.
Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Impaired episodic memory in PTSD patients - A meta-analysis of 47 studies.Frontiers in psychiatry · 2022Pooled it
- A sleep schedule incorporating naps benefits the transformation of hierarchical knowledge.Sleep · 2022Trial
- Task-relevant representational spaces in human memory traces.PLoS computational biology · 2025Article
- The neural underpinnings of aphantasia: a case study of identical twins.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- The Neural Underpinnings of Aphantasia: A Case Study of Identical Twins.bioRxiv : the preprint server for biology · 2025Article
- Interaction of repetition and retention interval influences the transfer effect after answer feedback for episodic memory.Frontiers in psychology · 2025Article
- Distributed and gradual microstructure changes are associated with the emergence of behavioural benefit from memory reactivation.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Selective Modulation of Fear Memory in Non-Rapid Eye Movement Sleep.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Repetition dynamically and rapidly increases cortical, but not hippocampal, offline reactivation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Recalled through this day but forgotten next week?-retrieval activity predicts durability of partly consolidated memories.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Representational formats of human memory traces.Brain structure & function · 2024Review
- Sleep and retrieval practice both strengthen and distort story recollection.Sleep advances : a journal of the Sleep Research Society · 2024Article
- Cueing memory reactivation during NREM sleep engenders long-term plasticity in both brain and behaviour.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Locating causal hubs of memory consolidation in spontaneous brain network in male mice.Nature communications · 2023Article
- Better late than never: sleep still supports memory consolidation after prolonged periods of wakefulness.Learning & memory (Cold Spring Harbor, N.Y.) · 2023Article
- The relationship between processing speed and remodeling spatial patterns of intrinsic brain activity in the elderly with different sleep duration.Frontiers in neuroscience · 2023Article
- On the Application of Developmental Cognitive Neuroscience in Educational Environments.Brain sciences · 2022Article
- A model of autonomous interactions between hippocampus and neocortex driving sleep-dependent memory consolidation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The Assimilation of Novel Information into Schemata and Its Efficient Consolidation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Discernible effects of tDCS over the primary motor and posterior parietal cortex on different stages of motor learning.Brain structure & function · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
After encoding, memories undergo a transitional process termed systems memory consolidation. It allows fast acquisition of new information by the hippocampus, as well as stable storage in neocortical long-term networks, where memory is protected from interference. Whereas this process is generally thought to occur slowly over time and sleep, we recently found a rapid memory systems transition from hippocampus to posterior parietal cortex (PPC) that occurs over repeated rehearsal within one study session. Here, we use fMRI to demonstrate that this transition is stabilized over sleep, whereas wakefulness leads to a reset to naïve responses, such as observed during early encoding. The role of sleep therefore seems to go beyond providing additional rehearsal through memory trace reactivation, as previously thought. We conclude that repeated study induces systems consolidation, while sleep ensures that these transformations become stable and long lasting. Thus, sleep and repeated rehearsal jointly contribute to long-term memory consolidation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.