Evidence map›Paper›PMID 31032342›Full record

ArticleBioMed research international2019

Gender Differences in Cardiovascular Risk Profile in Rheumatoid Arthritis Patients with Low Disease Activity.

Bożena Targońska-Stępniak, Małgorzata Biskup, Wojciech Biskup, Maria Majdan

Abstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Cardiovascular Implications of Immune Disorders in Women.Circulation research · 2022 · on this map
    Review
  10. Article
  11. Article
  12. Review
  13. Cardiovascular disease and subclinical atherosclerosis in rheumatoid arthritis.Hypertension research : official journal of the Japanese Society of Hypertension · 2020
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bożena Targońska-StępniakDepartment of Rheumatology and Connective Tissue Diseases, Medical University of Lublin, Lublin, Poland.ORCID 0000-0003-3916-4291
Małgorzata BiskupWojewódzki Zespół Specjalistyczny, Rzeszów, Poland.
Wojciech BiskupWojewódzki Zespół Specjalistyczny, Rzeszów, Poland.
Maria MajdanDepartment of Rheumatology and Connective Tissue Diseases, Medical University of Lublin, Lublin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePatients with rheumatoid arthritis (RA) have an excess risk of cardiovascular (CV) disease (CVD). The objective of the study was to compare CV risk profile in female and male RA patients with low disease activity. MATERIALS AND

methodsThe study group consisted of 70 RA patients with continuous low disease activity and no CVD (54 women, 16 men) and 33 healthy controls of comparable age. The groups were assessed for blood pressure, serum amino-terminal pro-brain natriuretic peptide (NT-proBNP), carotid intima media thickness (cIMT), electrocardiography, ejection fraction (EF), and diastolic dysfunction (DD).

resultsSignificantly higher burden of atherosclerosis, as revealed by higher cIMT, was found in males [0.93 (0.2) mm] vs females [0.80 (0.2) mm]. The risk of 10-year CVD was significantly higher in men than in women with RA. High/very high risk of fatal CVD was found in 62.5% of male patients. Males were significantly more often current/ex-smokers and had lower HDL-cholesterol and higher atherogenic index. There were no significant differences in NT-proBNP, QTc duration, and parameters of EF and DD.

conclusionsIn RA patients with continued low disease activity, a higher burden of atherosclerosis was found in males than in females. The data suggest a significant impact of traditional CV risk factors.

Indexed as

Risk AssessmentArthritis, RheumatoidBlood PressureCardiovascular DiseasesCardiovascular SystemCarotid Intima-Media ThicknessFemaleHumansMaleMiddle AgedNatriuretic Peptide, BrainPeptide FragmentsRisk FactorsSex CharacteristicsStroke VolumeNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)

Identifiers

PMID31032342
PMCPMC6458929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.