Evidence map›Paper›PMID 31032147›Full record

ArticleClinical psychological science : a journal of the Association for Psychological Science2019

Quantitative analysis of heterogeneity in academic achievement of children with autism.

Lang Chen, Daniel A Abrams, Miriam Rosenberg-Lee, Teresa Iuculano, Holly N Wakeman, Sandhya Prathap, Tianwen Chen, Vinod Menon

Abstract read
In one paragraph

Article in Clinical psychological science : a journal of the Association for Psychological Science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Counting, Cardinality and Conservation in Autistic Children.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lang ChenDepartment of Psychiatry and Behavioral Sciences, Stanford University.
Daniel A AbramsDepartment of Psychiatry and Behavioral Sciences, Stanford University.
Miriam Rosenberg-LeeDepartment of Psychiatry and Behavioral Sciences, Stanford University.
Teresa IuculanoDepartment of Psychiatry and Behavioral Sciences, Stanford University.
Holly N WakemanDepartment of Psychiatry and Behavioral Sciences, Stanford University.
Sandhya PrathapDepartment of Psychiatry and Behavioral Sciences, Stanford University.
Tianwen ChenDepartment of Psychiatry and Behavioral Sciences, Stanford University.
Vinod MenonDepartment of Psychiatry and Behavioral Sciences, Stanford University.

Funding

Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
Interventions in Math Learning Disabilities: Cognitive and Neural CorrelatesR01HD059205 · NICHD · STANFORD UNIVERSITY · PI Vinod Menon · 2009 to 2026
$10.8M
Mathematical Cognition in Autism: A Cognitive and Systems Neuroscience ApproachR01MH084164 · NIMH · STANFORD UNIVERSITY · PI MENON, VINOD · 2011 to 2021
$6.7M
Decoding Neural Systems Underlying Affective Prosody in Children with AutismK01MH102428 · NIMH · STANFORD UNIVERSITY · PI ABRAMS, DANIEL ARTHUR · 2014 to 2016
$525k
NCATS NIH HHS UL1 TR001085NICHD NIH HHS R01 HD059205NIMH NIH HHS K01 MH102428NIMH NIH HHS R01 MH084164
6 · The paper itself

Abstract

Autism spectrum disorders (ASD) represent a quintessential example of a clinical population with diverse symptom presentations and marked variation in cognitive abilities. However, the extent literature lacks rigorous quantitative procedures for characterizing heterogeneity of cognitive abilities in these individuals. Here we employ novel clustering and cross-validation procedures to investigate the stability of heterogeneous patterns of cognitive abilities in reading and math in a relatively large sample (N=114) of children with ASD and matched controls (N=96). Our analysis revealed a unique profile of heterogeneity in ASD, consisting of a low-achieving subgroup with poor math skills compared to reading, and a high-achieving subgroup who showed superior math skills compared to reading. Verbal and central executive working memory skills further differentiated these subgroups. Findings provide insights into distinct profiles of academic achievement in children with ASD, with implications for educational practice and intervention, and provide a novel framework for quantifying heterogeneity in the disorder.

Identifiers

PMID31032147
PMCPMC6483392

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.