Evidence map›Paper›PMID 31032146›Full record

ReviewJournal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B2019

Review Article: Synthesis, properties, and applications of fluorescent diamond particles.

Olga A Shenderova, Alexander I Shames, Nicholas A Nunn, Marco D Torelli, Igor Vlasov, Alexander Zaitsev

Abstract readReview
In one paragraph

Review in Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Probing Cellular Activity Via Charge-Sensitive Quantum Nanoprobes.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  5. Review
  6. Engineering spin coherence in core-shell diamond nanocrystals.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Timing and Mechanisms of Nanodiamond Uptake in Colon Cancer Cells.Nanotechnology, science and applications · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Clot Imaging Using Photostable Nanodiamond.Nanomaterials (Basel, Switzerland) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olga A ShenderovaAdámas Nanotechnologies, 8100 Brownleigh Dr., Raleigh, North California 27617.
Alexander I ShamesDepartment of Physics, Ben-Gurion University of the Negev, Be'er-Sheva 8410501, Israel.
Nicholas A NunnAdámas Nanotechnologies, 8100 Brownleigh Dr., Raleigh, North California 27617.
Marco D TorelliAdámas Nanotechnologies, 8100 Brownleigh Dr., Raleigh, North California 27617.
Igor VlasovGeneral Physics Institute, RAS, Vavilov Street 38, 119991 Moscow, Russia.
Alexander ZaitsevCollege of Staten Island, CUNY, 2800 Victory Blvd., Staten Island, New York 10312.

Funding

Fluorescent Nanodiamonds for Multiplexed Imaging and DiagnosticsR43CA232901 · NCI · ADAMAS NANOTECHNOLOGIES, INC. · PI BACKER, JOSEPH M, SHENDEROVA, OLGA A · 2018 to 2019
$346k
NCI NIH HHS R43 CA232901NHLBI NIH HHS HHSN268201500010C
6 · The paper itself

Abstract

Diamond particles containing color centers-fluorescent crystallographic defects embedded within the diamond lattice-outperform other classes of fluorophores by providing a combination of unmatched photostability, intriguing coupled magneto-optical properties, intrinsic biocompatibility, and outstanding mechanical and chemical robustness. This exceptional combination of properties positions fluorescent diamond particles as unique fluorophores with emerging applications in a variety of fields, including bioimaging, ultrasensitive metrology at the nanoscale, fluorescent tags in industrial applications, and even potentially as magnetic resonance imaging contrast agents. However, production of fluorescent nanodiamond (FND) is nontrivial, since it requires irradiation with high-energy particles to displace carbon atoms and create vacancies-a primary constituent in the majority color centers. In this review, centrally focused on material developments, major steps of FND production are discussed with emphasis on current challenges in the field and possible solutions. The authors demonstrate how the combination of fluorescent spectroscopy and electron paramagnetic resonance provides valuable insight into the types of radiation-induced defects formed and their evolution upon thermal annealing, thereby guiding FND performance optimization. A recent breakthrough process allowing for production of fluorescent diamond particles with vibrant blue, green, and red fluorescence is also discussed. Finally, the authors conclude with demonstrations of a few FND applications in the life science arena and in industry.

Identifiers

PMID31032146
PMCPMC6461556

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.