Evidence map›Paper›PMID 31031906›Full record

ArticleParkinson's disease2019

Psychometric Properties of the Apathy Scale in Advanced Parkinson's Disease.

John B Wetmore, José Matías Arbelo, María José Catalán, Francesc Valldeoriola, Carmen Rodriguez-Blazquez, Pablo Martinez-Martin

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Parkinson's disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02289729 (Study on Patient- and Caregiver-reported Symptoms and Outcomes With Levodopa/Carbidopa Intestinal Gel for the Treatment of Advanced Parkinson's Disease), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02289729 completednot on this map

Study on Patient- and Caregiver-reported Symptoms and Outcomes With Levodopa/Carbidopa Intestinal Gel for the Treatment of Advanced Parkinson's Disease

TypeobservationalSponsorAbbVieRan2014 to 2016Enrolled62ConditionsParkinson's Disease
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

John B WetmoreNational Center of Epidemiology, Carlos III Institute of Health, Madrid 28029, Spain.
José Matías ArbeloMovement Disorders Unit, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria 35016, Spain.
María José CatalánDepartment of Neurology, Hospital Clínico San Carlos, Madrid 28040, Spain.
Francesc ValldeoriolaDepartment of Neurology, Hospital Clínico de Barcelona, Barcelona 08036, Spain.
Carmen Rodriguez-BlazquezNational Center of Epidemiology, Carlos III Institute of Health, Madrid 28029, Spain.
Pablo Martinez-MartinNational Center of Epidemiology, Carlos III Institute of Health, Madrid 28029, Spain.ORCID 0000-0003-0837-5280
Instituto de Salud Carlos III · ESCity University of New York · USHospital Clínic de Barcelona · ESHospital Clínico San Carlos · ESHospital Universitario Insular de Gran Canaria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the psychometric attributes of the Apathy Scale- (AS-) Spanish version in patients with advanced Parkinson's disease (APD). MATERIALS AND

methodsOver 6 months, 61 patients participated in a clinical study of levodopa-carbidopa intestinal gel (LCIG) and were evaluated using the AS and other clinical tools. Various psychometric attributes of the AS were assessed.

resultsPatients (60.7% men) were aged 68.02 ± 7.43 years, with 12.57 ± 5.97 years from PD diagnosis. Median HY of patients in "on state" was 2 (range, 1-4), and mean levodopa equivalent daily dose was 1455.98 ± 456.00 mg. Overall, the parameters of feasibility/acceptability were satisfactory, except for a moderate-to-high floor effect in AS items but not in its total score (both 3.3%). Cronbach's alpha was 0.78, while item homogeneity coefficient was 0.21. Almost all items (11/14) reached acceptable item-total corrected correlations (

conclusionsThe AS showed satisfactory feasibility, acceptability, scaling assumptions, internal consistency, and convergent validity. Responsiveness parameters were poor, probably due to the characteristics of the clinical study from which these data came. This trial is registered with NCT02289729.

Identifiers

PMID31031906
PMCPMC6458845
OpenAlexW2928227404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.