Evidence map›Paper›PMID 31031755›Full record

ArticleFrontiers in immunology2019

Autophagy Limits Inflammasome During

Timothy R Crother, Rebecca A Porritt, Jargalsaikhan Dagvadorj, Gantsetseg Tumurkhuu, Anatoly V Slepenkin, Ellena M Peterson, Shuang Chen, Kenichi Shimada, Moshe Arditi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Frontiers in neuroscience · 2024
    Review
  5. Autophagy: the misty lands ofFrontiers in cellular and infection microbiology · 2024
    Review
  6. Article
  7. [Type III secretory protein SINC ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023
    Article
  8. Article
  9. Article
  10. Alternative strategies forFrontiers in microbiology · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Frontiers in immunology · 2021
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Timothy R CrotherDivision of Pediatric Infectious Diseases and Immunology, Department of Pediatrics, and Infectious and Immunological Diseases Research Center, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Rebecca A PorrittDivision of Pediatric Infectious Diseases and Immunology, Department of Pediatrics, and Infectious and Immunological Diseases Research Center, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Jargalsaikhan DagvadorjDivision of Pediatric Infectious Diseases and Immunology, Department of Pediatrics, and Infectious and Immunological Diseases Research Center, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Gantsetseg TumurkhuuDivision of Pediatric Infectious Diseases and Immunology, Department of Pediatrics, and Infectious and Immunological Diseases Research Center, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Anatoly V SlepenkinDepartment of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, CA, United States.
Ellena M PetersonDepartment of Pathology, University of California, Irvine, Irvine, CA, United States.
Shuang ChenDivision of Pediatric Infectious Diseases and Immunology, Department of Pediatrics, and Infectious and Immunological Diseases Research Center, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Kenichi ShimadaDivision of Pediatric Infectious Diseases and Immunology, Department of Pediatrics, and Infectious and Immunological Diseases Research Center, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Moshe ArditiDivision of Pediatric Infectious Diseases and Immunology, Department of Pediatrics, and Infectious and Immunological Diseases Research Center, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Cedars-Sinai Medical Center · USUniversity of California, Los Angeles · USUniversity of California, Irvine · US

Funding

Interaction with Rip2 and Th17 in Chronic InflammationR01AI117968 · NIAID · CEDARS-SINAI MEDICAL CENTER · PI ARDITI, MOSHE · 2016 to 2020
$2.3M
The role of the inflammasome in plasmacytoid dendritic cells during bacterial infectionR21AI112826 · NIAID · CEDARS-SINAI MEDICAL CENTER · PI CROTHER, TIMOTHY ROBERT · 2015 to 2016
$481k
Innate Immunity and Host Responses in Pathogenesis of Chlamydia PneumoniaeR56AI067995 · NIAID · CEDARS-SINAI MEDICAL CENTER · PI ARDITI, MOSHE · 2012 to 2012
$413k
NIAID NIH HHS R01 AI117968NIAID NIH HHS R21 AI112826NIAID NIH HHS R56 AI067995
6 · The paper itself

Abstract

Autophagy can either antagonize or promote intracellular bacterial growth, depending on the pathogen. Here, we investigated the role of autophagy during a pulmonary infection with the obligate intracellular pathogen,

Indexed as

AutophagyAnimalsBiomarkersChlamydophila InfectionsChlamydophila pneumoniaeFibroblastsFlow CytometryGene Knockout TechniquesInflammasomesMacrophagesMiceBiomarkersInflammasomesautophagyChlamydia pneumoniaeIL-1βinflammasomemacrophages

Identifiers

PMID31031755
PMCPMC6473188
OpenAlexW2939346431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.