Evidence map›Paper›PMID 31031714›Full record

ArticleFrontiers in microbiology2019

Membrane Sphingolipids Regulate the Fitness and Antifungal Protein Susceptibility of

Anna Huber, Gregor Oemer, Nermina Malanovic, Karl Lohner, Laura Kovács, Willi Salvenmoser, Johannes Zschocke, Markus A Keller, Florentine Marx

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
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  6. Article
  7. TheJournal of fungi (Basel, Switzerland) · 2022
    Article
  8. Phenotype to genotype inCurrent research in microbial sciences · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Membrane-Interacting Antifungal Peptides.Frontiers in cell and developmental biology · 2021
    Review
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Anna HuberDivision of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Gregor OemerDivision of Human Genetics, Medical University of Innsbruck, Innsbruck, Austria.
Nermina MalanovicInstitute of Molecular Biosciences, Biophysics Division, University of Graz, Graz, Austria.
Karl LohnerInstitute of Molecular Biosciences, Biophysics Division, University of Graz, Graz, Austria.
Laura KovácsDivision of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Willi SalvenmoserInstitute of Zoology, University of Innsbruck, Innsbruck, Austria.
Johannes ZschockeDivision of Human Genetics, Medical University of Innsbruck, Innsbruck, Austria.
Markus A KellerDivision of Human Genetics, Medical University of Innsbruck, Innsbruck, Austria.
Florentine MarxDivision of Molecular Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Universität Innsbruck · ATInnsbruck Medical University · ATUniversity of Graz · AT

Funding

Austrian Science Fund FWF I 1644
6 · The paper itself

Abstract

The membrane sphingolipid glucosylceramide (GlcCer) plays an important role in fungal fitness and adaptation to most diverse environments. Moreover, reported differences in the structure of GlcCer between fungi, plants and animals render this pathway a promising target for new generation therapeutics. Our knowledge about the GlcCer biosynthesis in fungi is mainly based on investigations of yeasts, whereas this pathway is less well characterized in molds. We therefore performed a detailed lipidomic profiling of GlcCer species present in

Indexed as

antimicrobial proteinsglucosylceramidelipidomicsNeurospora crassaPenicillium chrysogenumsphingolipids

Identifiers

PMID31031714
PMCPMC6471014
OpenAlexW2939874406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.